Dihydropteroate synthase 3D structures

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*DHPS binary complexes
*DHPS binary complexes
- 
**[[1ad4]] – SaDHPS + pterin-pyrophosphate<br />
**[[1ad4]] – SaDHPS + pterin-pyrophosphate<br />
-
**[[1aj2]] – EcDHPS + dihydro-pterin-methanyl-phosphonophosphate<br />
+
**[[1aj2]], [[7tq1]] – EcDHPS + pterin derivative
**[[5u0v]] - EcDHPS + nitrosoisocytosine inhibitor<br />
**[[5u0v]] - EcDHPS + nitrosoisocytosine inhibitor<br />
**[[5u0w]], [[5u0y]], [[5u0z]], [[5u11]], [[5u12]], [[5u13]], [[5u14]], [[5v79]], [[5v7a]] - EcDHPS + guanine inhibitor<br />
**[[5u0w]], [[5u0y]], [[5u0z]], [[5u11]], [[5u12]], [[5u13]], [[5u14]], [[5v79]], [[5v7a]] - EcDHPS + guanine inhibitor<br />
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**[[6pz2]] - DHPS + pteroic acid – ''Clostridioides difficile''<br />
**[[6pz2]] - DHPS + pteroic acid – ''Clostridioides difficile''<br />
**[[6ucz]] - DHPS + pterin derivative – ''Anaplasma phagocytophilum''<br />
**[[6ucz]] - DHPS + pterin derivative – ''Anaplasma phagocytophilum''<br />
 +
**[[7l6p]] - DHPS + imidazole – ''Stenotrophomonas maltophilia''<br />
 +
**[[8d5g]], [[8d5h]] - ubDHPS + pterin derivative – uncultured bacteria<br />
*DHPS ternary complexes
*DHPS ternary complexes
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**[[3tzf]] - YpDHPS + sulfa derivative + hydroxymethylpterin-diphosphate<br />
**[[3tzf]] - YpDHPS + sulfa derivative + hydroxymethylpterin-diphosphate<br />
**[[6q62]] - XaDHPS + indole carboxylate + chloroguanine<br />
**[[6q62]] - XaDHPS + indole carboxylate + chloroguanine<br />
 +
**[[8d5i]] - ubDHPS + pterin derivative + PPi<br />
-
*Bifunctional 6-hydroxymethyl-7,8-dihydropterin pyrophsphokinase-DHPS
+
*7,8-dihydro-6-hydroxymethylpterin pyrophsphokinase-DHPS
 +
**[[2bmb]] - HPPK-DHPS + pterin-methyl-phosphate – yeast<br />
**[[3mcm]], [[3mcn]] – FtPPPK-DHPS – ''Francisella tulerensis''<br />
**[[3mcm]], [[3mcn]] – FtPPPK-DHPS – ''Francisella tulerensis''<br />
**[[3mco]] - FtPPPK-DHPS + amino-hydroxymethyl-dihydro-pteridinone + methyladenosine triphosphate<br />
**[[3mco]] - FtPPPK-DHPS + amino-hydroxymethyl-dihydro-pteridinone + methyladenosine triphosphate<br />
-
**[[2bmb]] - PPPK-DHPS + pterin-methyl-phosphate - yeast
+
**[[4pzv]] – FtHPPK-DHPS + inhibitor<br />
 +
**[[6jwr]], [[6jws]], [[6jwu]], [[6jwx]] – PfHPPK-DHPS + AMP + pteridine derivative – ''Plasmodium falciparum''<br />
 +
**[[6jws]], [[6jwt]], [[6jwv]], [[6jww]], [[6jwy]], [[6jwz]] – PfHPPK-DHPS (mutant) + ATP + pteridine derivative<br />
 +
**[[6jwq]] – PfHPPK-DHPS + AMP + ATP<br />
 +
**[[6kck]] – PfHPPK-DHPS + AMP + hydroxybenzoate <br />
 +
**[[6kcl]], [[6kcm]] – PfHPPK-DHPS (mutant) + AMP + hydroxybenzoate <br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D structures of dihydropteroate synthase

Updated on 06-April-2025

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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