Dihydropteroate synthase 3D structures
From Proteopedia
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**[[1ad4]] – SaDHPS + pterin-pyrophosphate<br /> | **[[1ad4]] – SaDHPS + pterin-pyrophosphate<br /> | ||
| - | **[[1aj2]] – EcDHPS + | + | **[[1aj2]], [[7tq1]] – EcDHPS + pterin derivative |
**[[5u0v]] - EcDHPS + nitrosoisocytosine inhibitor<br /> | **[[5u0v]] - EcDHPS + nitrosoisocytosine inhibitor<br /> | ||
**[[5u0w]], [[5u0y]], [[5u0z]], [[5u11]], [[5u12]], [[5u13]], [[5u14]], [[5v79]], [[5v7a]] - EcDHPS + guanine inhibitor<br /> | **[[5u0w]], [[5u0y]], [[5u0z]], [[5u11]], [[5u12]], [[5u13]], [[5u14]], [[5v79]], [[5v7a]] - EcDHPS + guanine inhibitor<br /> | ||
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**[[5jq9]] - YpDHPS + sulfonamide inhibitor<br /> | **[[5jq9]] - YpDHPS + sulfonamide inhibitor<br /> | ||
**[[4o1e]], [[4o1f]] – DhDHPS + tetrahydrofolate derivative<br /> | **[[4o1e]], [[4o1f]] – DhDHPS + tetrahydrofolate derivative<br /> | ||
| - | ** | + | **[[6day]] - XaDHPS + PABA – ''Xanthomonas albilineans''<br /> |
**[[6ofw]] - XaDHPS + dihydro-pteroate<br /> | **[[6ofw]] - XaDHPS + dihydro-pteroate<br /> | ||
**[[6omz]] - DHPS + pterin-monophosphate – ''Mycobacterium smegmatis''<br /> | **[[6omz]] - DHPS + pterin-monophosphate – ''Mycobacterium smegmatis''<br /> | ||
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**[[6ucz]] - DHPS + pterin derivative – ''Anaplasma phagocytophilum''<br /> | **[[6ucz]] - DHPS + pterin derivative – ''Anaplasma phagocytophilum''<br /> | ||
**[[7l6p]] - DHPS + imidazole – ''Stenotrophomonas maltophilia''<br /> | **[[7l6p]] - DHPS + imidazole – ''Stenotrophomonas maltophilia''<br /> | ||
| + | **[[8d5g]], [[8d5h]] - ubDHPS + pterin derivative – uncultured bacteria<br /> | ||
*DHPS ternary complexes | *DHPS ternary complexes | ||
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**[[3tzf]] - YpDHPS + sulfa derivative + hydroxymethylpterin-diphosphate<br /> | **[[3tzf]] - YpDHPS + sulfa derivative + hydroxymethylpterin-diphosphate<br /> | ||
**[[6q62]] - XaDHPS + indole carboxylate + chloroguanine<br /> | **[[6q62]] - XaDHPS + indole carboxylate + chloroguanine<br /> | ||
| + | **[[8d5i]] - ubDHPS + pterin derivative + PPi<br /> | ||
*7,8-dihydro-6-hydroxymethylpterin pyrophsphokinase-DHPS | *7,8-dihydro-6-hydroxymethylpterin pyrophsphokinase-DHPS | ||
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**[[3mcm]], [[3mcn]] – FtPPPK-DHPS – ''Francisella tulerensis''<br /> | **[[3mcm]], [[3mcn]] – FtPPPK-DHPS – ''Francisella tulerensis''<br /> | ||
**[[3mco]] - FtPPPK-DHPS + amino-hydroxymethyl-dihydro-pteridinone + methyladenosine triphosphate<br /> | **[[3mco]] - FtPPPK-DHPS + amino-hydroxymethyl-dihydro-pteridinone + methyladenosine triphosphate<br /> | ||
| - | **[[6jwr]], [[6jws]], [[6jwx]] – PfHPPK-DHPS + AMP + pteridine derivative – ''Plasmodium falciparum''<br /> | + | **[[4pzv]] – FtHPPK-DHPS + inhibitor<br /> |
| + | **[[6jwr]], [[6jws]], [[6jwu]], [[6jwx]] – PfHPPK-DHPS + AMP + pteridine derivative – ''Plasmodium falciparum''<br /> | ||
**[[6jws]], [[6jwt]], [[6jwv]], [[6jww]], [[6jwy]], [[6jwz]] – PfHPPK-DHPS (mutant) + ATP + pteridine derivative<br /> | **[[6jws]], [[6jwt]], [[6jwv]], [[6jww]], [[6jwy]], [[6jwz]] – PfHPPK-DHPS (mutant) + ATP + pteridine derivative<br /> | ||
**[[6jwq]] – PfHPPK-DHPS + AMP + ATP<br /> | **[[6jwq]] – PfHPPK-DHPS + AMP + ATP<br /> | ||
Current revision
3D structures of dihydropteroate synthase
Updated on 06-April-2025
