9dn5
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 9dn5 is ON HOLD Authors: Kendrick, A.A., Leschziner, A.E. Description: CryoEM structures of yeast cytoplasmic dynein in the presence of ATP and Lis...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==CryoEM structures of yeast cytoplasmic dynein in the presence of ATP and Lis1.== | |
| - | + | <StructureSection load='9dn5' size='340' side='right'caption='[[9dn5]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9dn5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DN5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DN5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dn5 OCA], [https://pdbe.org/9dn5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dn5 RCSB], [https://www.ebi.ac.uk/pdbsum/9dn5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dn5 ProSAT]</span></td></tr> |
| - | [[Category: Kendrick | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DYHC_YEAST DYHC_YEAST] Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required to maintain uniform nuclear distribution in hyphae. May play an important role in the proper orientation of the mitotic spindle into the budding daughter cell yeast. Probably required for normal progression of the cell cycle.<ref>PMID:15642746</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae]] | ||
| + | [[Category: Kendrick AA]] | ||
| + | [[Category: Leschziner AE]] | ||
Current revision
CryoEM structures of yeast cytoplasmic dynein in the presence of ATP and Lis1.
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