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8uhg

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Current revision (09:11, 4 June 2025) (edit) (undo)
 
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== Function ==
== Function ==
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[https://www.uniprot.org/uniprot/NELFE_HUMAN NELFE_HUMAN] Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.<ref>PMID:10199401</ref> <ref>PMID:11940650</ref> <ref>PMID:12612062</ref>
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[https://www.uniprot.org/uniprot/NELFD_HUMAN NELFD_HUMAN] Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.<ref>PMID:10199401</ref> <ref>PMID:12612062</ref>
== References ==
== References ==
<references/>
<references/>

Current revision

Structure of paused transcription complex Pol II-DSIF-NELF - poised post-translocated

PDB ID 8uhg

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