Aldose reductase 3D structures

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*Aldose Reductase
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*Aldose Reductase or aldo-keto reductase family 1 member B1 or AKR1B1
**[[1abn]], [[1ads]], [[3q65]] - hAldR +NADP – human<br />
**[[1abn]], [[1ads]], [[3q65]] - hAldR +NADP – human<br />
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**[[2bgq]] – bAldR - barley<br />
**[[2bgq]] – bAldR - barley<br />
**[[2bgs]] - bAldR+NADP<br />
**[[2bgs]] - bAldR+NADP<br />
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**[[5jh1]], [[5jgy]] – maAldR – maize<br />
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**[[5jh1]], [[9ou1]] – maAldR – maize<br />
**[[5jgw]] – maAldR + NADP<br />
**[[5jgw]] – maAldR + NADP<br />
**[[5zci]] – DnAldR – ''Debaryomyces nepalensis''<br />
**[[5zci]] – DnAldR – ''Debaryomyces nepalensis''<br />
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*Aldose Reductase+inhibitors
*Aldose Reductase+inhibitors
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**[[3ghr]], [[3ghs]], [[3ght]], [[3ghu]], [[2r24]], [[2pzn]], [[3g5e]], [[2qxw]], [[2iki]], [[2i16]], [[2i17]], [[1t40]], [[1t41]], [[1us0]], [[1el3]], [[3t42]], [[4ys1]], [[4rpq]], [[4qr6]], [[4qbx]], [[4q7b]], [[2pev]], [[2pf8]], [[2pfh]], [[4puw]], [[4puu]] - hAldR +NADP+IDD inhibitors<br />
+
**[[1el3]], [[1t40]], [[1t41]], [[1us0]], [[2iki]], [[2i16]], [[2i17]], [[2pev]], [[2pf8]], [[2pfh]], [[2pzn]], [[2qxw]], [[2r24]], [[3g5e]], [[3ghr]], [[3ghs]], [[3ght]], [[3ghu]], [[3t42]], [[4puw]], [[4puu]], [[4q7b]], [[4qbx]], [[4qr6]], [[4rpq]], [[4ys1]] - hAldR +NADP+IDD inhibitors<br />
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**[[3onb]], [[3onc]], [[2pdk]], [[1az1]] – hAldR (mutant) +NADP+IDD inhibitor<br />
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**[[6t3p]], [[6t7q]], [[6td8]], [[6txp]], [[6xum]], [[6y1p]] [[8auu]], [[8b34]], [[8b3n]], [[8b3r]], [[8cnf]], [[8cnp]], [[8oz2]], [[8p2r]] - hAldR (mutant) +NADP+IDD inhibitor + citrate
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**[[3u2c]] - hAldR +NADP+ NSAID inhibitor<br />
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**[[1az1]], [[2pdc]], [[2pd]]j, [[2pdk]], [[2pdp]], [[2pdu]], [[3lbo]], [[3ld5]], [[3lep]], [[3lqg]], [[3lql]], [[3lz3]], [[3lz5]], [[3m4h]], [[3m64]], [[3mc5]], [[3onb]], [[3onc]], [[8b66]] - hAldR (mutant)+ NADP + IDD inhibitor
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**[[3bcj]], [[1x97]], [[1x98]], [[1pwm]], [[1ef3]], [[2pd5]], [[2dux]], [[2duz]], [[2dv0]], [[2fz8]], [[2fz9]], [[2hv5]], [[2hvn]], [[2hvo]], [[1mar]], [[2fzb]], [[2fzd]], [[1z3n]], [[1pwl]], [[1iei]], [[4jir]] - hAldR+NADP+inhibitor for diabetic treatment<br />
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**[[3u2c]] - hAldR +NADP+ NSAID inhibitor
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**[[1z89]], [[1z8a]] - hAldR+NADP+sulfonyl-pyridazinone<br />
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**[[1ef3]], [[1iei]], [[1mar]], [[1pwl]], [[1pwm]], [[1x97]], [[1x98]], [[1z3n]], [[2dux]], [[2duz]], [[2dv0]], [[2fz8]], [[2fz9]], [[2fzb]], [[2fzd]], [[2hv5]], [[2hvn]], [[2hvo]], [[2pd5]], [[3bcj]], [[4jir]] - hAldR+NADP+inhibitor for diabetic treatment<br />
 +
**[[2agt]], [[2pd9]], [[2pdb]], [[2pdf]], [[2pdi]], [[2pdl]], [[2pdm]], [[2pdw]], [[2pdx]], [[2pdy]], [[3len]], [[3m0i]], [[3mb9]] – hAldR (mutant) + NADP + inhibitor for diabetic treatment
 +
**[[1z89]], [[1z8a]] - hAldR+NADP+sulfonyl-pyridazinone
**[[5ha7]] – hAldR (mutant) +NADP+pyrimidine inhibitor<br />
**[[5ha7]] – hAldR (mutant) +NADP+pyrimidine inhibitor<br />
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**[[4yu1]], [[4prt]], [[4prr]], [[4pr4]], [[4nkc]] – hAldR +NADP+ diphenyl inhibitor<br />
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**[[4nkc]], [[4pr4]], [[4prr]], [[4prt]], [[4yu1]] – hAldR +NADP+ diphenyl inhibitor<br />
**[[5ouj]], [[5ouk]] – hAldR + NADP+ quinoine inhibitor<br />
**[[5ouj]], [[5ouk]] – hAldR + NADP+ quinoine inhibitor<br />
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**[[2pdg]], [[2pdh]], [[4xzi]], [[4xzh]] - hAldR+NADP+uracil inhibitor<br />
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**[[2pdg]], [[2pdh]], [[4xzi]], [[4xzh]] - hAldR+NADP+uracil inhibitor
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**[[1x96]], [[2acs]], [[2acu]], [[6f7r]], [[6f81]], [[6f82]], [[6f84]], [[6f8o]] - hAldR+NADP+citrate<br />
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**[[1x96]], [[2acs]], [[2acu]], [[6f7r]], [[6f81]], [[6f82]], [[6f84]], [[6f8o]] - hAldR+NADP+citrate
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**[[2acq]] - hAldR +NADP+glucose phosphate<br />
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**[[2acq]] - hAldR +NADP+glucose phosphate
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**[[2acr]] - hAldR +NADP+cacodylate<br />
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**[[2acr]] - hAldR +NADP+cacodylate
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**[[2ikg]], [[2ikh]], [[2ikj]], [[3v35]] - hAldR+NADP+nitro-substituted inhibitor<br />
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**[[2ikg]], [[2ikh]], [[2ikj]], [[3v35]] - hAldR+NADP+nitro-substituted inhibitor
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**[[3v36]] - hAldR+NADP+ glyceraldehyde + azine<br />
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**[[3v36]] - hAldR+NADP+ glyceraldehyde + azine
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**[[2nvc]], [[2nvd]] - hAldR+NADP+isothiazole inhibitor<br />
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**[[2nvc]], [[2nvd]] - hAldR+NADP+isothiazole inhibitor
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**[[3p2v]] - hAldR+NADP+ benzothiazepine inhibitor<br />
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**[[3p2v]] - hAldR+NADP+ benzothiazepine inhibitor
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**[[2ipw]], [[2iq0]], [[2iqd]], [[2isf]], [[2ine]], [[2inz]], [[2is7]] - hAldR+NADP+ acid<br />
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**[[2ine]], [[2inz]], [[2ipw]], [[2iq0]], [[2iqd]], [[2is7]], [[2isf]] - hAldR+NADP+ acid<br />
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**[[2f2k]] - hAldR+NADP+DEG<br />
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**[[2f2k]] - hAldR+NADP+DEG
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**[[2pdn]], [[2pdq]] – hAldR (mutant)+NADP+uracil inhibitor<br />
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**[[2pdn]], [[2pdq]] – hAldR (mutant)+NADP+uracil inhibitor
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**[[2pdb]], [[2pdf]], [[2pdi]], [[2pdm]], [[2pdx]], [[3len]], [[3m0i]], [[3mb9]], [[2pd9]], [[2pdw]], [[2pdy]], [[2agt]], [[2pdl]] – hAldR (mutant)+NADP+inhibitor for diabetic treatment<br />
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**[[1az2]], [[6t27]], [[6t5g]], [[6y03]], [[8a4n]], [[8aqg]], [[8aqp]] - hAldR (mutant)+NADP+citrate
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**[[1az2]], [[6t27]], [[6t5g]], [[6y03]] - hAldR (mutant)+NADP+citrate<br />
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**[[3dn5]] – hAldR+NADP+biaryl inhibitor
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**[[3lbo]], [[3ld5]], [[3lql]], [[3lz5]], [[2pdc]], [[3lep]], [[3lqg]], [[3lz3]], [[3m4h]], [[2pdj]], [[2pdp]], [[2pdu]], [[3m64]], [[3mc5]], [[6t3p]], [[6t7q]], [[6td8]], [[6txp]], [[6xum]], [[6y1p]] - hAldR (mutant)+IDD inhibitors<br />
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**[[3dn5]] – hAldR+NADP+biaryl inhibitor<br />
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**[[3rx2]], [[3rx3]], [[3rx4]], [[3s3g]] - hAldR+NADP+ sulindac inhibitor<br />
**[[3rx2]], [[3rx3]], [[3rx4]], [[3s3g]] - hAldR+NADP+ sulindac inhibitor<br />
**[[4igs]] - hAldR+NADP+ polyfluorinated inhibitor<br />
**[[4igs]] - hAldR+NADP+ polyfluorinated inhibitor<br />
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**[[8ae9]], [[8bjl]], [[8fh5]], [[8fh6]], [[8fh7]], [[8fh9]] - hAldR+NADP + inhibitor<br />
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**[[8fh8]] - hAldR+NADP+ H2O2 + inhibitor<br />
**[[4lau]], [[4laz]], [[4lb3]], [[4lb4]], [[4lbr]], [[4lbs]], [[4qxi]], [[6syw]], [[6tuc]], [[6tuf]] - hAldR+NADP+ carbamoyl inhibitor<br />
**[[4lau]], [[4laz]], [[4lb3]], [[4lb4]], [[4lbr]], [[4lbs]], [[4qxi]], [[6syw]], [[6tuc]], [[6tuf]] - hAldR+NADP+ carbamoyl inhibitor<br />
**[[4qx4]] - hAldR+NADP+ mercaptotriazinoindole inhibitor<br />
**[[4qx4]] - hAldR+NADP+ mercaptotriazinoindole inhibitor<br />
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**[[3fx4]] – pAldR+NADP+thiazolidine derivative <br />
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**[[3fx4]] – pAldR+NADP+thiazolidine derivative
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**[[1eko]], [[1ah0]], [[3h4g]], [[1ah3]], [[1ae4]] - pAldR+NADP+IDD inhibitor<br />
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**[[1ae4]], [[1ah0]], [[1ah3]], [[1eko]], [[3h4g]] - pAldR+NADP+IDD inhibitor
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**[[2vdg]] – bAldR+NADP+butanol <br />
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**[[2vdg]] – bAldR+NADP+butanol
**[[5jh2]] – maAldR + adenosine diphosphate <br />
**[[5jh2]] – maAldR + adenosine diphosphate <br />
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}}
}}
[[Category: Topic Page]]
[[Category: Topic Page]]

Current revision

3D Structures of Aldose Reductase

Updated on 03-July-2025

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky

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