Galactosidase 3D structures

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*α-Galactosidase
*α-Galactosidase
-
**[[3hg2]], [[3gxn]], [[1r46]], [[1r47]], [[3s5y]], [[3s5z]] – hAgal A - human<br />
+
**[[1r46]], [[1r47]], [[3gxn]], [[3hg2]], [[3s5y]], [[3s5z]] – hAgal A - human<br />
**[[3lx9]], [[3lxa]], [[3lxb]], [[3lxc]], [[3tv8]] - hAgal A (mutant) <br />
**[[3lx9]], [[3lxa]], [[3lxb]], [[3lxc]], [[3tv8]] - hAgal A (mutant) <br />
**[[3h53]] - hAgal B (mutant)<br />
**[[3h53]] - hAgal B (mutant)<br />
Line 20: Line 20:
**[[4fnp]] – GsAgal (mutant) – ''Geobacillus stearothermophilus''<br />
**[[4fnp]] – GsAgal (mutant) – ''Geobacillus stearothermophilus''<br />
**[[4fnq]], [[4fnr]], [[4oif]] – GsAgal<br />
**[[4fnq]], [[4fnr]], [[4oif]] – GsAgal<br />
-
**[[4xpo]] - PsBgal – ''Pedobacter saltans'' <br />
+
**[[4xpo]] - PsAgal – ''Pedobacter saltans'' <br />
**[[4xpr]] - PsAgal (mutant)<br />
**[[4xpr]] - PsAgal (mutant)<br />
**[[6f4c]] - Agal – ''Nicotiana benthamiana''<br />
**[[6f4c]] - Agal – ''Nicotiana benthamiana''<br />
Line 27: Line 27:
**[[6phu]] – SpAgal – ''Streptococcus pneumoniae<''br />
**[[6phu]] – SpAgal – ''Streptococcus pneumoniae<''br />
**[[6y2k]] - Agal – ''Marinomonas''<br />
**[[6y2k]] - Agal – ''Marinomonas''<br />
 +
**[[8k1a]], [[8k7u]] – BpAgal – ''Blautia pseudococcoides''<br />
 +
**[[8j50]] – FpAgal – ''Flavihumibacter petaseus''<br />
 +
**[[8j53]] - Agal – ''Bacterioides salyersiae''<br />
-
*''α-galactosidase binary complex''
+
*''α-galactosidase binary complex with galactose''
-
**[[3h54]] - hAgal B (mutant) + polysaccharide<br />
+
**[[3gxp]] - hAgal A + galactose<br />
 +
**[[3hg3]], [[3hg5]] - hAgal A (mutant) + galactose<br />
**[[3h55]] - hAgal B (mutant) + galactose<br />
**[[3h55]] - hAgal B (mutant) + galactose<br />
 +
**[[1t0o]] – HjAgal + galactose<br />
 +
**[[2xn2]] - LaAgal + galactose<br />
 +
**[[4xpp]] - PsAgal + galactose<br />
 +
**[[8j51]] - FpAgal + galactose <br />
 +
 +
*''α-galactosidase other binary complexes''
 +
 +
**[[3h54]] - hAgal B (mutant) + polysaccharide<br />
**[[3igu]] - hAgal B (mutant) + intermediate<br />
**[[3igu]] - hAgal B (mutant) + intermediate<br />
-
**[[3hg3]], [[3hg5]] - hAgal A (mutant) + galactose<br />
+
**[[9avs]] - hAgal A (mutant) + saposin<br />
-
**[[3gxp]] - hAgal A + galactose<br />
+
**[[3hg4]] – hAgal A + intermediate<br />
**[[3hg4]] – hAgal A + intermediate<br />
-
**[[3gxt]] – hAgal A + imino sugar<br />
+
**[[3gxt]], [[8k7d]], [[8k7e]], [[8k7f]], [[8k7g]], [[8k7h]], [[8k7i]], [[8k7j]], [[8k7k]], [[8k7l]] – hAgal A + imino sugar<br />
**[[4nxs]] - hAgal + jirimycin derivative<br />
**[[4nxs]] - hAgal + jirimycin derivative<br />
**[[6ibk]], [[6ibm]], [[6ibr]], [[6ibt]] - hAgal A + trisaccharide + cyclosulfamidate<br />
**[[6ibk]], [[6ibm]], [[6ibr]], [[6ibt]] - hAgal A + trisaccharide + cyclosulfamidate<br />
**[[7exq]], [[7exr]] - Agal + saccharide – ''Arabidopsis thaliana''<br />
**[[7exq]], [[7exr]] - Agal + saccharide – ''Arabidopsis thaliana''<br />
-
**[[1t0o]] – HjAgal + galactose<br />
 
-
**[[2xn2]] - LaAgal + galactose<br />
 
-
**[[4xpp]] - PsAgal + galactose<br />
 
**[[4xpq]] - PsAgal + fucose<br />
**[[4xpq]] - PsAgal + fucose<br />
**[[4xps]] - PsAgal (mutant) + galactopyranoside derivative<br />
**[[4xps]] - PsAgal (mutant) + galactopyranoside derivative<br />
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**[[4fnt]], [[4fnu]] – GsAgal + galactoside<br />
**[[4fnt]], [[4fnu]] – GsAgal + galactoside<br />
**[[5e1q]] - BtAgal + Gal-Lac<br />
**[[5e1q]] - BtAgal + Gal-Lac<br />
-
**[[5m12]], [[5m16]], [[5m1i]], [[6gx8]], [[6gwg]], [[6gvd]] - TmAgal + sugar<br />
+
**[[5m12]], [[5m16]], [[5m1i]], [[6gx8]], [[6gvd]], [[6gwg]] - TmAgal + sugar<br />
-
**[[6gwf]], [[6gta]] - TmAgal (mutant) + sugar<br />
+
**[[6gta]], [[6gwf]] - TmAgal (mutant) + sugar<br />
**[[6lck]], [[6lcl]] - TtAgal + saccharide<br />
**[[6lck]], [[6lcl]] - TtAgal + saccharide<br />
**[[6phv]] - SpAgal + galactopyranoside derivative<br />
**[[6phv]] - SpAgal + galactopyranoside derivative<br />
**[[6phw]], [[6phx]], [[6phy]], [[6pi0]] - SpAgal (mutant) + oligosaccharide<br />
**[[6phw]], [[6phx]], [[6phy]], [[6pi0]] - SpAgal (mutant) + oligosaccharide<br />
 +
**[[8k7v]] – BpAgal 5 + inhibitor<br />
 +
**[[8j52]] - FpAgal + galactobiose <br />
 +
 +
*Alpha-1,3-Galactosidase
 +
 +
**[[8yk1]], [[8yk2]], [[8yk3]] – BbAgal - ''Bifidobacterium bifidum''<br />
 +
**[[9i4f]] - PpAgal – ''Pedobacter panaciterae'' <br />
 +
**[[9i4g]] - PpAgal + galactose<br />
*β-Galactosidase
*β-Galactosidase
Line 59: Line 75:
**[[5iaz]] - rBgal C-terminal - NMR<br />
**[[5iaz]] - rBgal C-terminal - NMR<br />
**[[3og2]] – TrBgal – ''Trichoderma reesei''<br />
**[[3og2]] – TrBgal – ''Trichoderma reesei''<br />
-
**[[1hn1]], [[1dp0]], [[1f4a]], [[1f4h]], [[4v41]], [[4v40]], [[4ttg]], [[6drv]] - EcBgal - ''Escherichia coli''<br />
+
**[[1dp0]], [[1f4a]], [[1f4h]], [[1hn1]], [[4v40]], [[4v41]], [[4ttg]], [[6drv]] - EcBgal - ''Escherichia coli''<br />
-
**[[3muy]], [[3i3e]], [[3iap]], [[3iaq]], [[3dym]], [[3dyp]], [[1px3]], [[3sep]], [[3t0a]], [[3t2o]], [[3vd3]], [[3vd5]], [[3vda]], [[4duv]] – EcBgal (mutant)<br />
+
**[[1px3]], [[3dym]], [[3dyp]], [[3i3e]], [[3iap]], [[3iaq]], [[3muy]], [[3sep]], [[3t0a]], [[3t2o]], [[3vd3]], [[3vd5]], [[3vda]], [[4duv]] – EcBgal (mutant)<br />
-
**[[3j7h]], [[6cvm]], [[6drv]], [[6x1q]] – EcBgal – cryo EM<br />
+
**[[3j7h]], [[6cvm]], [[6drv]], [[6x1q]], [[8bk7]], [[8bk8]], [[8bkg]], [[8q7y]], [[8vt0]] – EcBgal – cryo EM<br />
-
**[[3dec]], [[3d3a]], [[3bga]], [[5mt2]], [[5mui]], [[5muj]], [[6euf]], [[6euj]] – BtBgal<br />
+
**[[3bga]], [[3d3a]], [[3dec]], [[5mt2]], [[5mui]], [[5muj]], [[6euf]], [[6euj]] – BtBgal<br />
**[[6etz]], [[6h1p]], [[6zjv]] - ArBgal – ''Arthrobacter''<br />
**[[6etz]], [[6h1p]], [[6zjv]] - ArBgal – ''Arthrobacter''<br />
**[[1yq2]], [[6se8]], [[6zjp]] - ArBgal (mutant)<br />
**[[1yq2]], [[6se8]], [[6zjp]] - ArBgal (mutant)<br />
**[[1uwi]], [[4eam]], [[5i3d]] - SsBgal (mutant) - ''Sulfolobus solfataricus''<br />
**[[1uwi]], [[4eam]], [[5i3d]] - SsBgal (mutant) - ''Sulfolobus solfataricus''<br />
-
**[[1uwq]], [[1gow]] – SsBgal<br />
+
**[[1gow]], [[1uwq]] – SsBgal<br />
**[[1kwg]] – TtBgal – ''Thermus thermophilus''<br />
**[[1kwg]] – TtBgal – ''Thermus thermophilus''<br />
**[[1tg7]] – PeBgal – ''Penicillium''<br />
**[[1tg7]] – PeBgal – ''Penicillium''<br />
-
**[[3tts]], [[4mad]], [[7cwi]] – BcBgal – ''Bacillus circulans''<br />
+
**[[3tts]], [[4mad]], [[7cwi]], [[8q2h]], [[8q4y]] – BcBgal – ''Bacillus circulans''<br />
**[[4ypj]] - BcBgal (mutant) <br />
**[[4ypj]] - BcBgal (mutant) <br />
**[[4ha3]], [[4ha4]] – Bgal – ''Acidilobus saccharovorans''<br />
**[[4ha3]], [[4ha4]] – Bgal – ''Acidilobus saccharovorans''<br />
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**[[4uoq]] - BaBgal (mutant) <br />
**[[4uoq]] - BaBgal (mutant) <br />
**[[5vym]] - Bgal – ''Bifidobacterium adolescentis''<br />
**[[5vym]] - Bgal – ''Bifidobacterium adolescentis''<br />
-
**[[5nav]], [[5naq]] - Bgal – ''Lactobacillus plantarum''<br />
+
**[[5naq]], [[5nav]] - Bgal – ''Lactobacillus plantarum''<br />
**[[5yhs]] - BacBgal – ''Bacillus'' <br />
**[[5yhs]] - BacBgal – ''Bacillus'' <br />
**[[3ob8]], [[3oba]] – Bgal – ''Kluyveromyces lactis''<br />
**[[3ob8]], [[3oba]] – Bgal – ''Kluyveromyces lactis''<br />
**[[5dfa]] - GsBgal (mutant) <br />
**[[5dfa]] - GsBgal (mutant) <br />
-
**[[5dmy]], [[6quc]], [[7nit]] - BbBgal – ''Bifidobacterium bifidum''<br />
+
**[[5dmy]], [[6quc]], [[7nit]] - BbBgal <br />
**[[5e9a]] - Bgal - ''Rahnella''<br />
**[[5e9a]] - Bgal - ''Rahnella''<br />
**[[5euv]] - ParBgal - ''Paracoccus''<br />
**[[5euv]] - ParBgal - ''Paracoccus''<br />
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**[[7f1n]] - Bgal - ''Thermofilum''<br />
**[[7f1n]] - Bgal - ''Thermofilum''<br />
**[[7sf2]] - Bgal – ''Bacterioides cellulosilyticus''<br />
**[[7sf2]] - Bgal – ''Bacterioides cellulosilyticus''<br />
 +
**[[8u7f]], [[8u7g]] - Bgal - ''Cuniculiplasma divulgatum''<br />
 +
**[[8oi4]] - Bgal – organismal metagenome<br />
 +
**[[8z43]], [[8z47]], [[8z48]] – Bgal – ''Bacterioides xylanisolvens'' <br />
 +
**[[8ibr]] - BlBgal (mutant) – ''Bifidobacterium longum''<br />
 +
**[[8qqh]], [[8uid]] – Bgal – ''Desulfurococcus amylolyticus''<br />
 +
**[[8oug]] – Bgal – ''Thermococcus chitonophagus''<br />
 +
**[[8h25]] – Bgal – ''Lacticaseibacillus casei''<br />
 +
**[[8fa4]], [[8fa5]], [[8faa]] – Bgal – ''Xanthomonas campestris''<br />
 +
**[[9m0e]] – Bgal – ''Paenibacillus barengoltzii''<br />
*''β-Galactosidase binary complex with galactose''
*''β-Galactosidase binary complex with galactose''
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**[[1kwk]] – TtBgal + galactose<br />
**[[1kwk]] – TtBgal + galactose<br />
**[[3ogr]] – TrBgal + galactose<br />
**[[3ogr]] – TrBgal + galactose<br />
-
**[[3e1f]], [[1jz7]] - EcBgal (mutant) + galactose<br />
+
**[[1jz7]], [[3e1f]] - EcBgal (mutant) + galactose<br />
**[[3t09]], [[3t0d]], [[3t2q]], [[3vd7]], [[3vdb]] - EcBgal (mutant) + galactose derivative<br />
**[[3t09]], [[3t0d]], [[3t2q]], [[3vd7]], [[3vdb]] - EcBgal (mutant) + galactose derivative<br />
**[[4iug]] - Bgal + galactose – ''Aspergillus oryzae''<br />
**[[4iug]] - Bgal + galactose – ''Aspergillus oryzae''<br />
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**[[7kmo]] - XcBgal + galactose <br />
**[[7kmo]] - XcBgal + galactose <br />
**[[6eui]] - BtBgal + galactose<br />
**[[6eui]] - BtBgal + galactose<br />
 +
**[[8ibs]] - BlBgal (mutant) + galactose <br />
*''β-Galactosidase other complexes''
*''β-Galactosidase other complexes''
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**[[3ogs]] - TrBgal + IPTG<br />
**[[3ogs]] - TrBgal + IPTG<br />
**[[3ogv]] – TrBgal + inhibitor<br />
**[[3ogv]] – TrBgal + inhibitor<br />
-
**[[2ceq]], [[1uwr]], [[1uws]], [[1uwt]], [[1uwu]], [[2cer]] - SsBgal + inhibitor<br />
+
**[[1uwr]], [[1uws]], [[1uwt]], [[1uwu]], [[2ceq]], [[2cer]] - SsBgal + inhibitor<br />
**[[4ean]], [[5ixe]] – SsBgal + indole derivative<br />
**[[4ean]], [[5ixe]] – SsBgal + indole derivative<br />
-
**[[3muz]], [[3i3d]], [[3dyo]], [[1px4]], [[1jyx]], [[3t08]], [[3t0b]], [[3t2p]], [[3vd4]], [[3vd9]], [[3vdc]]- EcBgal (mutant) + IPTG<br />
+
**[[1jyx]], [[1px4]], [[3dyo]], [[3i3d]], [[3muz]], [[3t08]], [[3t0b]], [[3t2p]], [[3vd4]], [[3vd9]], [[3vdc]]- EcBgal (mutant) + IPTG<br />
-
**[[3mv0]], [[3i3b]], [[3czj]], [[4v45]], [[1jz2]], [[1jz3]], [[1jz4]], [[1jz5]], [[1jz6]] - EcBgal (mutant) + intermediate<br />
+
**[[1jz2]], [[1jz3]], [[1jz4]], [[1jz5]], [[1jz6]], [[3czj]], [[3i3b]], [[3mv0]], [[4v45]] - EcBgal (mutant) + intermediate<br />
**[[3mv1]] - EcBgal (mutant) + guanidinium<br />
**[[3mv1]] - EcBgal (mutant) + guanidinium<br />
-
**[[1jyn]], [[4v44]], [[1jz8]] - EcBgal (mutant) + lactose derivative<br />
+
**[[1jyn]], [[1jz8]], [[4v44]] - EcBgal (mutant) + lactose derivative<br />
-
**[[1jyn]], [[1jyw]], [[1jyv]] - EcBgal (mutant) + substrate<br />
+
**[[1jyn]], [[1jyv]], [[1jyw]] - EcBgal (mutant) + substrate<br />
**[[5a1a]] - EcBgal + inhibitor – Cryo-EM<br />
**[[5a1a]] - EcBgal + inhibitor – Cryo-EM<br />
**[[1jz6]] - EcBgal (mutant) + inhibitor<br />
**[[1jz6]] - EcBgal (mutant) + inhibitor<br />
**[[4duw]] - EcBgal (mutant) + allolactose<br />
**[[4duw]] - EcBgal (mutant) + allolactose<br />
**[[6tsk]] - EcBgal + ribose – Cryo EM<br />
**[[6tsk]] - EcBgal + ribose – Cryo EM<br />
 +
**[[8ri6]], [[8ri7]], [[8ri8]] - EcBgal + imino sugar – Cryo EM<br />
**[[4dux]] - EcBgal (mutant) + ribose<br />
**[[4dux]] - EcBgal (mutant) + ribose<br />
**[[6tte]] - EcBgal + galactopyranoside derivative – Cryo EM<br />
**[[6tte]] - EcBgal + galactopyranoside derivative – Cryo EM<br />
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**[[4d1j]] - CjBgal + drug <br />
**[[4d1j]] - CjBgal + drug <br />
**[[5ift]], [[5ihr]], [[5juv]] - AnBgal (mutant) + saccharide<br />
**[[5ift]], [[5ihr]], [[5juv]] - AnBgal (mutant) + saccharide<br />
 +
**[[7uz1]], [[7uz2]] - Bgal (mutant) + inhibitor – ''Saccharolobus solfataricus''<br />
 +
**[[8ibt]] - BlBgal (mutant) + tetraose <br />
*Endo-1,4-β-galactosidase
*Endo-1,4-β-galactosidase
Line 196: Line 225:
*6-phospho-β-D-galactosidase
*6-phospho-β-D-galactosidase
-
**[[2pbg]], [[3pbg]], [[4pbg]], [[1pbg]] – Pgal (mutant) – ''Lactococcus lacti''<br />
+
**[[1pbg]], [[2pbg]], [[3pbg]], [[4pbg]] – Pgal (mutant) – ''Lactococcus lacti''<br />
**[[2v4v]] – gal GH59 – ''Clostridium cellulolyticum''<br />
**[[2v4v]] – gal GH59 – ''Clostridium cellulolyticum''<br />
**[[4zep]] – GsPgal + phospho-glucose<br />
**[[4zep]] – GsPgal + phospho-glucose<br />

Current revision

3D Structures of Galactosidase

Updated on 08-July-2025

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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