9kyl
From Proteopedia
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(New page: '''Unreleased structure''' The entry 9kyl is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human TRIP4 in complex with 11bp dsDNA== | |
| - | + | <StructureSection load='9kyl' size='340' side='right'caption='[[9kyl]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9kyl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KYL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kyl OCA], [https://pdbe.org/9kyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kyl RCSB], [https://www.ebi.ac.uk/pdbsum/9kyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kyl ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TRIP4_HUMAN TRIP4_HUMAN] Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function (By similarity).<ref>PMID:12077347</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Guo WT]] | ||
| + | [[Category: Meng CY]] | ||
| + | [[Category: Wen Y]] | ||
| + | [[Category: Wu BX]] | ||
Current revision
Crystal structure of human TRIP4 in complex with 11bp dsDNA
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Categories: Homo sapiens | Large Structures | Synthetic construct | Guo WT | Meng CY | Wen Y | Wu BX
