Inosine monophosphate dehydrogenase 3D structures

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Current revision (10:23, 18 September 2025) (edit) (undo)
 
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**[[1eep]] – IMPDH – ''Borellia burgdorferi'' <br />
**[[1eep]] – IMPDH – ''Borellia burgdorferi'' <br />
**[[1zfj]] – IMPDH catalytic domain – ''Streptococcus pyogenes'' <br />
**[[1zfj]] – IMPDH catalytic domain – ''Streptococcus pyogenes'' <br />
 +
**[[7xlo]] – IMPDH catalytic domain 1-97, 208-496 – ''Methanocaldococcus jannaschii'' <br />
**[[1vrd]] – IMPDH – ''Thermotoga maritima'' <br />
**[[1vrd]] – IMPDH – ''Thermotoga maritima'' <br />
**[[3ffs]] – CpIMPDH – ''Cryptosporidium parvum''<br />
**[[3ffs]] – CpIMPDH – ''Cryptosporidium parvum''<br />
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**[[4xwu]] – AgIMPDH (mutant) – ''Ashbya gossypii''<br />
**[[4xwu]] – AgIMPDH (mutant) – ''Ashbya gossypii''<br />
**[[6kcf]] – IMPDH – ''Liberibacter asiaticus'' <br />
**[[6kcf]] – IMPDH – ''Liberibacter asiaticus'' <br />
 +
**[[8pw3]] – MsIMPDH – ''Mycobacterium smegmatis'' – Cryo EM<br />
*IMPDH binary complex
*IMPDH binary complex
**[[1jcn]] – hMPDH 1 + IMP derivative - human<br />
**[[1jcn]] – hMPDH 1 + IMP derivative - human<br />
 +
**[[6udp]] – hMPDH 2 + IMP – Cryo EM <br />
**[[1jr1]] – hMPDH 2 + mycophenolic acid <br />
**[[1jr1]] – hMPDH 2 + mycophenolic acid <br />
**[[6i0m]] – hMPDH 2 + GDP<br />
**[[6i0m]] – hMPDH 2 + GDP<br />
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**[[2cu0]] – IMPDH + xanthosine monophosphate – ''Pyrococcus horikoshii''<br />
**[[2cu0]] – IMPDH + xanthosine monophosphate – ''Pyrococcus horikoshii''<br />
**[[5upx]] – LmIMPDH + xanthosine monophosphate – ''Listeria monocytogenes''<br />
**[[5upx]] – LmIMPDH + xanthosine monophosphate – ''Listeria monocytogenes''<br />
 +
**[[8ebc]] – LmIMPDH + IMP <br />
**[[3usb]] – BaIMPDH + IMP <br />
**[[3usb]] – BaIMPDH + IMP <br />
**[[6mgu]] – BaIMPDH + oxaosine monophosphate <br />
**[[6mgu]] – BaIMPDH + oxaosine monophosphate <br />
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**[[6d4q]], [[6d4r]], [[6d4s]], [[6d4t]], [[6d4u]], [[6d4v]], [[6d4w]], [[6mjy]] – IMPDH + inhibitor – ''Mycobacterium thermoresistibile''<br />
**[[6d4q]], [[6d4r]], [[6d4s]], [[6d4t]], [[6d4u]], [[6d4v]], [[6d4w]], [[6mjy]] – IMPDH + inhibitor – ''Mycobacterium thermoresistibile''<br />
**[[6lk4]] – TbIMPDH + GTP – ''Trypanosoma brucei''<br />
**[[6lk4]] – TbIMPDH + GTP – ''Trypanosoma brucei''<br />
 +
**[[8q65]], [[8qqw]] – MsIMPDH + ATP – Cryo EM<br />
*IMPDH ternary complex with inosinic acid (IMP) and inhibitor
*IMPDH ternary complex with inosinic acid (IMP) and inhibitor
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**[[5upv]] - MtIMPDH catalytic domain (mutant) + inhibitor + IMP <br />
**[[5upv]] - MtIMPDH catalytic domain (mutant) + inhibitor + IMP <br />
**[[5j5r]], [[5k4x]], [[5k4z]] - MrIMPDH + inhibitor + IMP – ''Mycobacterium thermoresistibile''<br />
**[[5j5r]], [[5k4x]], [[5k4z]] - MrIMPDH + inhibitor + IMP – ''Mycobacterium thermoresistibile''<br />
-
**[[5urr]], [[5urs]], [[5uuv]], [[5uuw]], [[5uuz]] – BaIMPDH catalytic domain + inhibitor + IMP <br />
+
**[[7mtx]], [[5urs]], [[5uuv]], [[7mtu]], [[5uuz]], [[7mtu]], [[7mtx]] – BaIMPDH catalytic domain + inhibitor + IMP <br />
**[[4my1]], [[4mya]], [[4my8]], [[4my9]], [[4qm1]] – BaIMPDH catalytic domain (mutant) + inhibitor + IMP <br />
**[[4my1]], [[4mya]], [[4my8]], [[4my9]], [[4qm1]] – BaIMPDH catalytic domain (mutant) + inhibitor + IMP <br />
**[[4mz1]], [[4mz8]] – CjIMPDH catalytic domain (mutant) + inhibitor + IMP <br />
**[[4mz1]], [[4mz8]] – CjIMPDH catalytic domain (mutant) + inhibitor + IMP <br />
Line 66: Line 71:
*IMPDH other ternary complexes
*IMPDH other ternary complexes
-
**[[6udp]] – hMPDH 2 + IMP – Cryo EM <br />
 
**[[6u8e]], [[6u8s]], [[6ua5]] – hMPDH 2 + NAD + IMP – Cryo EM <br />
**[[6u8e]], [[6u8s]], [[6ua5]] – hMPDH 2 + NAD + IMP – Cryo EM <br />
**[[6u8n]], [[6u8r]] – hMPDH 2 + NAD + ATP + IMP – Cryo EM <br />
**[[6u8n]], [[6u8r]] – hMPDH 2 + NAD + ATP + IMP – Cryo EM <br />
Line 87: Line 91:
**[[6rpu]] – AgIMPDH + AP5G + GDP<br />
**[[6rpu]] – AgIMPDH + AP5G + GDP<br />
**[[6rfu]] – TbIMPDH + ATP + GMP<br />
**[[6rfu]] – TbIMPDH + ATP + GMP<br />
 +
**[[9i0k]], [[9i0l]] – MsMPDH + NAD + IMP – Cryo EM <br />
 +
**[[8qqp]], [[8qqq]] – MsMPDH + ATP + GTP – Cryo EM <br />
 +
**[[8qqr]], [[8qqt]] – MsMPDH + ATP + ppGpp – Cryo EM <br />
 +
**[[8qqv]], [[8qqx]], [[9i0m]] – MsMPDH + ATP + IMP – Cryo EM <br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D structures of inosine monophosphate dehydrogenase

Updated on 18-September-2025

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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