Insulin-like growth factor
From Proteopedia
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Inhibition of IGF I influences colon cancer<ref>PMID:11694656</ref>. IGF I has protective effect in neuropathy<ref>PMID:15832492</ref>. | Inhibition of IGF I influences colon cancer<ref>PMID:11694656</ref>. IGF I has protective effect in neuropathy<ref>PMID:15832492</ref>. | ||
| - | See also [[Insulin-like growth factor receptor]]. | + | See also [[Insulin-like growth factor receptor]] and [[Insulin-like growth factor 1]]. |
</StructureSection> | </StructureSection> | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| + | * IGF I | ||
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| + | **[[8pyi]], [[8pyk]], [[8pym]], [[8pyn]] - hIGF I + inhibitor – human - Cryo EM<br /> | ||
| + | **[[8eyr]], [[8x06]], [[8x2m]], [[8xjs]], [[8xkm]], [[8xkr]] - hIGF I + IGFI receptor – Cryo EM<br /> | ||
*IGF I residues 49-118 | *IGF I residues 49-118 | ||
| - | **[[2gf1]], [[3gf1]], [[1b9g]], [[1bqt]], [[6rva]] – hIGF I | + | **[[2gf1]], [[3gf1]], [[1b9g]], [[1bqt]], [[6rva]] – hIGF I – NMR<BR /> |
**[[3lri]] - hIGF I (mutant) – NMR<BR /> | **[[3lri]] - hIGF I (mutant) – NMR<BR /> | ||
**[[1imx]], [[1gzr]], [[1gzy]], [[1gzz]], [[1h02]] - hIGF I<BR /> | **[[1imx]], [[1gzr]], [[1gzy]], [[1gzz]], [[1h02]] - hIGF I<BR /> | ||
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**[[7wrq]] - hIGF I + IGFBP3 + ALS – Cryo EM<br /> | **[[7wrq]] - hIGF I + IGFBP3 + ALS – Cryo EM<br /> | ||
**[[7s0q]] - hIGF I + IGFI receptor + insulin receptor – Cryo EM<br /> | **[[7s0q]] - hIGF I + IGFI receptor + insulin receptor – Cryo EM<br /> | ||
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| + | * IGF II | ||
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| + | **[[8u4c]], [[8u4e]], [[8vjb]], [[8vjc]], [[8ysz]] - hIGF II + insulin receptor – Cryo EM<br /> | ||
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*IGF II residues 25-91 | *IGF II residues 25-91 | ||
Current revision
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3D structures of insulin-like growth factor
Updated on 22-September-2025
References
- ↑ Wood AW, Duan C, Bern HA. Insulin-like growth factor signaling in fish. Int Rev Cytol. 2005;243:215-85. PMID:15797461 doi:http://dx.doi.org/10.1016/S0074-7696(05)43004-1
- ↑ Giovannucci E. Insulin, insulin-like growth factors and colon cancer: a review of the evidence. J Nutr. 2001 Nov;131(11 Suppl):3109S-20S. PMID:11694656
- ↑ Mohamed-Ali V, Pinkney J. Therapeutic potential of insulin-like growth factor-1 in patients with diabetes mellitus. Treat Endocrinol. 2002;1(6):399-410. PMID:15832492
