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<div style="top:+0.2em; font-size:1.2em; padding:5px 5px 5px 10px; float:right;">'''''ISSN 2310-6301'''''</div>
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Often it is difficult to utilize the wealth of information found in 3D biomacromolecular structures. Proteopedia's goal is to present structure/function information on these molecules in a user-friendly manner to a broad scientific audience.
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<b>Proteopedia</b> presents this information in a user-friendly way as a '''collaborative & free 3D-encyclopedia of proteins & other biomolecules.'''
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<th style="padding: 10px;background-color: #33ff7b">Selected Pages</th>
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<th style="padding: 10px;background-color: #33ff7b">Selected Research Pages</th>
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<th style="padding: 10px;background-color: #dae4d9">Art on Science</th>
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<th style="padding: 10px;background-color: #f1b840">In Journals</th>
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<th style="padding: 10px;background-color: #f1b840">Journals</th>
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<th style="padding: 10px;background-color: #79baff">Education</th>
<th style="padding: 10px;background-color: #79baff">Education</th>
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<p>[[Proteopedia:Video_Guide|Video Guides]]</p>
<p>[[Proteopedia:Video_Guide|Video Guides]]</p>
<p>[[Who knows]] ...</p>
<p>[[Who knows]] ...</p>
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<p>[[:Category:PDB Art|List of Art on Science pages]]</p>
 
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<td>[[Proteopedia:About|About]]</td>
<td>[[Proteopedia:About|About]]</td>
<td>[[Special:Contact|Contact]]</td>
<td>[[Special:Contact|Contact]]</td>
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<td>[[Template:MainPageNews|Hot News]]</td>
<td>[[Proteopedia:Table of Contents|Table of Contents]]</td>
<td>[[Proteopedia:Table of Contents|Table of Contents]]</td>
<td>[[Proteopedia:Structure Index|Structure Index]]</td>
<td>[[Proteopedia:Structure Index|Structure Index]]</td>

Current revision

ISSN 2310-6301

As life is more than 2D, Proteopedia helps to bridge the gap between 3D structure & function of biomacromolecules

Proteopedia presents this information in a user-friendly way as a collaborative & free 3D-encyclopedia of proteins & other biomolecules.


Selected Research Pages In Journals Education
About this image
Avian Influenza Neuraminidase

Eric Martz
The first new influenza virus to emerge as an imminent pandemic threat in the 21st century is H1N1 swine flu. The drug oseltamivir (Tamiflu®) inhibits flu neuraminidase, a component necessary for virus spread, in susceptible flu strains. The development of oseltamivir was guided, in part, by crystallographically determined structures of flu neuraminidase, which is a homotetramer, shown with oseltamivir bound. Oseltamivir was designed to fit N2/N9 (neuraminidases from other strains of flu). Serendipitously, it also fits N1 by induced fit.

>>> Visit this page >>>

About this image
Structure of Anticancer Ruthenium Half-Sandwich Complex Bound to Glycogen Synthase Kinase 3ß

G Atilla-Gocumen, L Di Costanzo, E Meggers. J Biol Inorg Chem. 2010 doi: 10.1007/s00775-010-0699-x
A crystal structure of an organometallic half-sandwich ruthenium complex bound to glycogen synthase kinase 3ß (GSK-3ß) reveals that the inhibitor binds to the ATP binding site via an induced fit mechanism utilizing several hydrogen bonds and hydrophobic interactions. Importantly, the metal is not involved in any direct interaction with the protein kinase but fulfills a purely structural role.

>>> Visit this I3DC complement >>>

About this image
Touch-Sensitive Channel

Touching stretches cell membranes, opening mechanosensitive ion channels, leading to sensation by the nervous system. Pictured is the transmembrane region of a similar channel in bacteria. When closed, the narrow opening is lined by hydrophobic amino acid sidechains, making it non-conductive to ions.

>>> See more animations and explanation >>>

How to add content to Proteopedia

Video Guides

Who knows ...

About Interactive 3D Complements - I3DCs

List of I3DCs

How to get an I3DC for your paper

Teaching strategies using Proteopedia

Examples of pages for teaching

How to add content to Proteopedia

About Contact Hot News Table of Contents Structure Index Help

Proteopedia Page Contributors and Editors (what is this?)

Joel L. Sussman, Jaime Prilusky

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