8z87
From Proteopedia
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(New page: '''Unreleased structure''' The entry 8z87 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the CHBA-bound human HCAR1-Gi1 complex== | |
| - | + | <StructureSection load='8z87' size='340' side='right'caption='[[8z87]], [[Resolution|resolution]] 2.73Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8z87]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z87 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.73Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1D71:3-chloranyl-5-oxidanyl-benzoic+acid'>A1D71</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z87 OCA], [https://pdbe.org/8z87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z87 RCSB], [https://www.ebi.ac.uk/pdbsum/8z87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z87 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HCAR1_HUMAN HCAR1_HUMAN] Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.<ref>PMID:19047060</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gao M]] | ||
| + | [[Category: Ma X]] | ||
| + | [[Category: Mao C]] | ||
| + | [[Category: Zang S]] | ||
| + | [[Category: Zhang Y]] | ||
| + | [[Category: Zhu Y]] | ||
Current revision
Cryo-EM structure of the CHBA-bound human HCAR1-Gi1 complex
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Categories: Homo sapiens | Large Structures | Gao M | Ma X | Mao C | Zang S | Zhang Y | Zhu Y
