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AR mediate the actions of testosterone (T) and a more biologically active form, 5α-dihydrotestosterone (DHT), which are the male sex hormones required for development of the male reproductive system and secondary sexual characteristics. This receptor, located on the X chromosome, is expressed in a diverse range of tissues, because they have significant biological actions in many systems <ref>PMID: 27057074</ref>. There are other androgens that bind with much less potency than T and DHT such as androstenedione, androstenediol, and dehydroepiandrosterone (DHEA) <ref>PMID: 36376977 </ref>.

=Structure=

<StructureSection load='3b5r' size='350' side='right' caption='AR' scene=''>

The androgen receptor (AR) belongs to the steroid hormone group nuclear receptor family with the estrogen, progesterone, glucocorticoid and mineralcorticoid receptor.

AR mediate the actions of testosterone and a more biologically active form, dihydrotestosterone (DHT), which are the male sex hormones required for development of the male reproductive system and secondary sexual characteristics. This receptor is expressed in a diverse range of tissues, because they have significant biological actions in many systems.

== Structure ==

<scene name='85/857155/H12_androgen_receptor/1'>H12</scene>

== Function ==

== Structural highlights ==

== 3D Structures of androgen receptor ==

==drugs==

<scene name='85/857155/Bicatulamide_in_ar/1'>bicatulamide</scene>