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1xl2

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[[Image:1xl2.gif|left|200px]]
[[Image:1xl2.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1xl2 |SIZE=350|CAPTION= <scene name='initialview01'>1xl2</scene>, resolution 1.50&Aring;
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The line below this paragraph, containing "STRUCTURE_1xl2", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=189:N-BENZYL-2-(2,6-DIMETHYLPHENOXY)-N-[((3R,4S)-4-{[ISOBUTYL(PHENYLSULFONYL)AMINO]METHYL}PYRROLIDIN-3-YL)METHYL]ACETAMIDE'>189</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
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-->
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|DOMAIN=
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{{STRUCTURE_1xl2| PDB=1xl2 | SCENE= }}
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|RELATEDENTRY=[[1hvi|1HVI]], [[1ajx|1AJX]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xl2 OCA], [http://www.ebi.ac.uk/pdbsum/1xl2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xl2 RCSB]</span>
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}}
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'''HIV-1 Protease in complex with pyrrolidinmethanamine'''
'''HIV-1 Protease in complex with pyrrolidinmethanamine'''
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[[Category: Klebe, G.]]
[[Category: Klebe, G.]]
[[Category: Specker, E.]]
[[Category: Specker, E.]]
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[[Category: aspartyl protease]]
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[[Category: Aspartyl protease]]
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[[Category: hiv protease]]
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[[Category: Hiv protease]]
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[[Category: pyrrolidine inhibitor]]
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[[Category: Pyrrolidine inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:10:16 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:51:17 2008''
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Revision as of 12:10, 3 May 2008

Image:1xl2.gif

Template:STRUCTURE 1xl2

HIV-1 Protease in complex with pyrrolidinmethanamine


About this Structure

1XL2 is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

An old target revisited: two new privileged skeletons and an unexpected binding mode for HIV-protease inhibitors., Specker E, Bottcher J, Lilie H, Heine A, Schoop A, Muller G, Griebenow N, Klebe G, Angew Chem Int Ed Engl. 2005 May 13;44(20):3140-4. PMID:15822136 Page seeded by OCA on Sat May 3 15:10:16 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

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