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1xoy

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[[Image:1xoy.gif|left|200px]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xoy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xoy OCA], [http://www.ebi.ac.uk/pdbsum/1xoy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xoy RCSB]</span>
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'''Solution structure of At3g04780.1, an Arabidopsis ortholog of the C-terminal domain of human thioredoxin-like protein'''
'''Solution structure of At3g04780.1, an Arabidopsis ortholog of the C-terminal domain of human thioredoxin-like protein'''
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[[Category: Center for eukaryotic structural genomic]]
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[[Category: cesg]]
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[[Category: protein structure initiative]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:18:52 2008''
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Revision as of 12:18, 3 May 2008

Template:STRUCTURE 1xoy

Solution structure of At3g04780.1, an Arabidopsis ortholog of the C-terminal domain of human thioredoxin-like protein


Overview

The structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein, was determined by NMR spectroscopy. The structure is dominated by a beta-barrel sandwich. A two-stranded anti-parallel beta-sheet, which seals off one end of the beta-barrel, is flanked by two flexible loops rich in acidic amino acids. Although this fold often provides a ligand binding site, the structure did not reveal an appreciable cavity inside the beta-barrel. The three-dimensional structure of At3g04780.1-des15 provides an entry point for understanding its functional role and those of its mammalian homologs.

About this Structure

1XOY is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

Solution structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein., Song J, Tyler RC, Wrobel RL, Frederick RO, Vojtek FC, Jeon WB, Lee MS, Markley JL, Protein Sci. 2005 Apr;14(4):1059-63. Epub 2005 Mar 1. PMID:15741346 Page seeded by OCA on Sat May 3 15:18:52 2008

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