2fgo

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{{Structure
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fgo OCA], [http://www.ebi.ac.uk/pdbsum/2fgo PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2fgo RCSB]</span>
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'''Structure of the 2[4FE-4S] ferredoxin from Pseudomonas aeruginosa'''
'''Structure of the 2[4FE-4S] ferredoxin from Pseudomonas aeruginosa'''
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[[Category: Mavridis, I M.]]
[[Category: Mavridis, I M.]]
[[Category: Pinotsis, N.]]
[[Category: Pinotsis, N.]]
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[[Category: [4fe-4s] cluster]]
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[[Category: Allochromatium vinosum]]
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[[Category: allochromatium vinosum]]
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[[Category: Ferredoxin]]
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[[Category: ferredoxin]]
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[[Category: Iron binding protein]]
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[[Category: iron binding protein]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: pseudomonas aeruginosa]]
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[[Category: Reduction potential]]
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[[Category: reduction potential]]
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Revision as of 00:52, 4 May 2008

Template:STRUCTURE 2fgo

Structure of the 2[4FE-4S] ferredoxin from Pseudomonas aeruginosa


Overview

The structure of the 2[4Fe-4S] ferredoxin (PaFd) from Pseudomonas aeruginosa, which belongs to the Allochromatium vinosum (Alvin) subfamily, has been determined by X-ray crystallography at 1.32-A resolution, which is the highest up to now for a member of this subfamily of Fds. The main structural features of PaFd are similar to those of AlvinFd. However, the significantly higher resolution of the PaFd structure makes possible a reliable comparison with available high-resolution structures of [4Fe-4S]-containing Fds, in an effort to rationalize the unusual electrochemical properties of Alvin-like Fds. Three major factors contributing to the reduction potential values of [4Fe-4S]2+/+ clusters of Fds, namely, the surface accessibility of the clusters, the N-H...S hydrogen-bonding network, and the volume of the cavities hosting the clusters, are extensively discussed. The volume of the cavities is introduced in the present work for the first time, and can in part explain the very negative potential of cluster I of Alvin-like Fds.

About this Structure

2FGO is a Single protein structure of sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

The structure of the 2[4Fe-4S] ferredoxin from Pseudomonas aeruginosa at 1.32-A resolution: comparison with other high-resolution structures of ferredoxins and contributing structural features to reduction potential values., Giastas P, Pinotsis N, Efthymiou G, Wilmanns M, Kyritsis P, Moulis JM, Mavridis IM, J Biol Inorg Chem. 2006 Jun;11(4):445-58. Epub 2006 Apr 5. PMID:16596388 Page seeded by OCA on Sun May 4 03:52:22 2008

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