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2nui

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[[Image:2nui.gif|left|200px]]
[[Image:2nui.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2nui |SIZE=350|CAPTION= <scene name='initialview01'>2nui</scene>, resolution 1.10&Aring;
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The line below this paragraph, containing "STRUCTURE_2nui", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_2nui| PDB=2nui | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nui OCA], [http://www.ebi.ac.uk/pdbsum/2nui PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2nui RCSB]</span>
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}}
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'''X-ray Structure of synthetic [D83A]RNase A'''
'''X-ray Structure of synthetic [D83A]RNase A'''
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==Overview==
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The total chemical synthesis of RNase A using modern chemical ligation methods is described, illustrating the significant advances that have been made in chemical protein synthesis since Gutte and Merrifield's pioneering preparation of RNase A in 1969. The identity of the synthetic product was confirmed through rigorous characterization, including the determination of the X-ray crystal structure to 1.1 Angstrom resolution. (c) 2007 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 90:278-286, 2008.This article was originally published online as an accepted preprint. The "Published Online" date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com.
==About this Structure==
==About this Structure==
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2NUI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NUI OCA].
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2NUI is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NUI OCA].
==Reference==
==Reference==
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Total synthesis by modern chemical ligation methods &amp; high resolution (1.1Angstrom) X-ray structure of ribonuclease A., Boerema DJ, Tereshko VA, Kent SB, Biopolymers. 2007 Jul 3;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17610259 17610259]
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Total synthesis by modern chemical ligation methods and high resolution (1.1 A) X-ray structure of ribonuclease A., Boerema DJ, Tereshko VA, Kent SB, Biopolymers. 2008;90(3):278-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17610259 17610259]
[[Category: Pancreatic ribonuclease]]
[[Category: Pancreatic ribonuclease]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Kent, S B.H.]]
[[Category: Kent, S B.H.]]
[[Category: Tereshko, V A.]]
[[Category: Tereshko, V A.]]
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[[Category: hydrolase]]
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[[Category: Hydrolase]]
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[[Category: synthetic protein]]
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[[Category: Synthetic protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 09:55:37 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:08:38 2008''
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Revision as of 06:55, 4 May 2008

Image:2nui.gif

Template:STRUCTURE 2nui

X-ray Structure of synthetic [D83A]RNase A


Overview

The total chemical synthesis of RNase A using modern chemical ligation methods is described, illustrating the significant advances that have been made in chemical protein synthesis since Gutte and Merrifield's pioneering preparation of RNase A in 1969. The identity of the synthetic product was confirmed through rigorous characterization, including the determination of the X-ray crystal structure to 1.1 Angstrom resolution. (c) 2007 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 90:278-286, 2008.This article was originally published online as an accepted preprint. The "Published Online" date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com.

About this Structure

2NUI is a Single protein structure. Full crystallographic information is available from OCA.

Reference

Total synthesis by modern chemical ligation methods and high resolution (1.1 A) X-ray structure of ribonuclease A., Boerema DJ, Tereshko VA, Kent SB, Biopolymers. 2008;90(3):278-86. PMID:17610259 Page seeded by OCA on Sun May 4 09:55:37 2008

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