This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Sandbox 8
From Proteopedia
| Line 6: | Line 6: | ||
| - | This model contains <scene name=' | + | This model contains <scene name='Sandbox_8/Ligand_kys/1'>the ruthenium ligant (KYS).</scene>. |
Revision as of 14:45, 23 May 2008
|
This is a T7-tagged full-length streptavidin complexed with ruthenium ligand.
Guided by the X-ray structure of an S-selective artificial transfer hydrogenase, designed evolution was used to optimize the selectivity of hybrid catalysts. Fine-tuning of the second coordination sphere of the ruthenium center (see picture, orange sphere) by introduction of two point mutations allowed the identification of selective artificial transfer hydrogenases for the reduction of dialkyl ketones.
This model contains .
