1a0b

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{{STRUCTURE_1a0b| PDB=1a0b | SCENE= }}
{{STRUCTURE_1a0b| PDB=1a0b | SCENE= }}
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'''HISTIDINE-CONTAINING PHOSPHOTRANSFER DOMAIN OF ARCB FROM ESCHERICHIA COLI'''
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===HISTIDINE-CONTAINING PHOSPHOTRANSFER DOMAIN OF ARCB FROM ESCHERICHIA COLI===
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==Overview==
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The histidine-containing phosphotransfer (HPt) domain is a novel protein module with an active histidine residue that mediates phosphotransfer reactions in the two-component signaling systems. A multistep phosphorelay involving the HPt domain has been suggested for these signaling pathways. The crystal structure of the HPt domain of the anaerobic sensor kinase ArcB has been determined at 2.06 A resolution. The domain consists of six alpha helices containing a four-helix bundle-folding. The pattern of sequence similarity of the HPt domains of ArcB and components in other signaling systems can be interpreted in light of the three-dimensional structure and supports the conclusion that the HPt domains have a common structural motif both in prokaryotes and eukaryotes.
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(as it appears on PubMed at http://www.pubmed.gov), where 9054511 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9054511}}
==About this Structure==
==About this Structure==
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[[Category: Phosphotransfer]]
[[Category: Phosphotransfer]]
[[Category: Two-component system]]
[[Category: Two-component system]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 09:37:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 15:42:45 2008''

Revision as of 12:42, 30 June 2008

Image:1a0b.png

Template:STRUCTURE 1a0b

HISTIDINE-CONTAINING PHOSPHOTRANSFER DOMAIN OF ARCB FROM ESCHERICHIA COLI

Template:ABSTRACT PUBMED 9054511

About this Structure

1A0B is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Insights into multistep phosphorelay from the crystal structure of the C-terminal HPt domain of ArcB., Kato M, Mizuno T, Shimizu T, Hakoshima T, Cell. 1997 Mar 7;88(5):717-23. PMID:9054511

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