1eo1

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{{STRUCTURE_1eo1| PDB=1eo1 | SCENE= }}
{{STRUCTURE_1eo1| PDB=1eo1 | SCENE= }}
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'''Solution structure of hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum'''
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===Solution structure of hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum===
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==Overview==
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The solution structure of MTH1175, a 124-residue protein from the archaeon Methanobacterium thermoautotrophicum has been determined by NMR spectroscopy. MTH1175 is part of a family of conserved hypothetical proteins (COG1433) with unknown functions which contains multiple paralogs from all complete archaeal genomes and the archaeal gene-rich bacterium Thermotoga maritima. Sequence similarity indicates this protein family may be related to the nitrogen fixation proteins NifB and NifX. MTH1175 adopts an alpha/beta topology with a single mixed beta-sheet, and contains two flexible loops and an unstructured C-terminal tail. The fold resembles that of Ribonuclease H and similar proteins, but differs from these in several respects, and is not likely to have a nuclease activity.
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(as it appears on PubMed at http://www.pubmed.gov), where 12836677 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12836677}}
==About this Structure==
==About this Structure==
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1EO1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EO1 OCA].
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1EO1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EO1 OCA].
==Reference==
==Reference==
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[[Category: Strand order 321456,strands 2 and 6 antiparallel to rest.]]
[[Category: Strand order 321456,strands 2 and 6 antiparallel to rest.]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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Revision as of 22:13, 30 June 2008

Image:1eo1.png

Template:STRUCTURE 1eo1

Solution structure of hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum

Template:ABSTRACT PUBMED 12836677

About this Structure

1EO1 is a Single protein structure of sequence from Methanothermobacter thermautotrophicus. Full experimental information is available from OCA.

Reference

NMR structure determination and structure-based functional characterization of conserved hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum., Cort JR, Yee A, Edwards AM, Arrowsmith CH, Kennedy MA, J Struct Funct Genomics. 2000;1(1):15-25. PMID:12836677

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