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1g90

From Proteopedia

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{{STRUCTURE_1g90| PDB=1g90 | SCENE= }}
{{STRUCTURE_1g90| PDB=1g90 | SCENE= }}
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'''NMR Solution Structure of Outer Membrane Protein A Transmembrane Domain: 10 conformers'''
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===NMR Solution Structure of Outer Membrane Protein A Transmembrane Domain: 10 conformers===
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==Overview==
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We have determined the three-dimensional fold of the 19 kDa (177 residues) transmembrane domain of the outer membrane protein A of Escherichia coli in dodecylphosphocholine (DPC) micelles in solution using heteronuclear NMR. The structure consists of an eight-stranded beta-barrel connected by tight turns on the periplasmic side and larger mobile loops on the extracellular side. The solution structure of the barrel in DPC micelles is similar to that in n-octyltetraoxyethylene (C(8)E(4)) micelles determined by X-ray diffraction. Moreover, data from NMR dynamic experiments reveal a gradient of conformational flexibility in the structure that may contribute to the membrane channel function of this protein.
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{{ABSTRACT_PUBMED_11276254}}
==About this Structure==
==About this Structure==
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1G90 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA].
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1G90 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA].
==Reference==
==Reference==
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[[Category: Integral membrane protein]]
[[Category: Integral membrane protein]]
[[Category: Nmr]]
[[Category: Nmr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 17:17:41 2008''
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Revision as of 01:54, 1 July 2008

Image:1g90.png

Template:STRUCTURE 1g90

NMR Solution Structure of Outer Membrane Protein A Transmembrane Domain: 10 conformers

Template:ABSTRACT PUBMED 11276254

About this Structure

1G90 is a Single protein structure of sequence from Escherichia coli. Full experimental information is available from OCA.

Reference

Structure of outer membrane protein A transmembrane domain by NMR spectroscopy., Arora A, Abildgaard F, Bushweller JH, Tamm LK, Nat Struct Biol. 2001 Apr;8(4):334-8. PMID:11276254

Page seeded by OCA on Tue Jul 1 04:54:27 2008

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