1gu2

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{{STRUCTURE_1gu2| PDB=1gu2 | SCENE= }}
{{STRUCTURE_1gu2| PDB=1gu2 | SCENE= }}
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'''CRYSTAL STRUCTURE OF OXIDIZED CYTOCHROME C" FROM METHYLOPHILUS METHYLOTROPHUS'''
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===CRYSTAL STRUCTURE OF OXIDIZED CYTOCHROME C" FROM METHYLOPHILUS METHYLOTROPHUS===
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==Overview==
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The crystal structures of the oxidized and reduced forms of cytochrome c" from Methylophilus methylotrophus were solved from X-ray synchrotron data to atomic resolution. The overall fold of the molecule in the two redox states is very similar and is comparable to that of the oxygen-binding protein from the purple phototrophic bacterium Rhodobacter sphaeroides. However, significant modifications occur near the haem group, in particular the detachment from axial binding of His95 observed upon reduction as well as the adoption of different conformations of some protonatable residues that form a possible proton path from the haem pocket to the protein surface. These changes are associated with the previously well characterized redox-Bohr behaviour of this protein. Furthermore they provide a model for one of the presently proposed mechanisms of proton translocation in the much more complex protein cytochrome c oxidase.
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(as it appears on PubMed at http://www.pubmed.gov), where 16341897 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16341897}}
==About this Structure==
==About this Structure==
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[[Category: Electron transport]]
[[Category: Electron transport]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:00:26 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:04:48 2008''

Revision as of 03:04, 1 July 2008

Image:1gu2.png

Template:STRUCTURE 1gu2

CRYSTAL STRUCTURE OF OXIDIZED CYTOCHROME C" FROM METHYLOPHILUS METHYLOTROPHUS

Template:ABSTRACT PUBMED 16341897

About this Structure

1GU2 is a Single protein structure of sequence from Methylophilus methylotrophus. Full crystallographic information is available from OCA.

Reference

Structural evidence for a proton transfer pathway coupled with haem reduction of cytochrome c" from Methylophilus methylotrophus., Enguita FJ, Pohl E, Turner DL, Santos H, Carrondo MA, J Biol Inorg Chem. 2006 Mar;11(2):189-96. Epub 2005 Dec 10. PMID:16341897

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