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1gw7

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[[Image:1gw7.gif|left|200px]]
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{{STRUCTURE_1gw7| PDB=1gw7 | SCENE= }}
{{STRUCTURE_1gw7| PDB=1gw7 | SCENE= }}
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'''QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 CAPSID, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY.'''
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===QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 CAPSID, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY.===
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==Overview==
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Bacteriophage PRD1 shares many structural and functional similarities with adenovirus. A major difference is the PRD1 internal membrane, which acts in concert with vertex proteins to translocate the phage genome into the host. Multiresolution models of the PRD1 capsid, together with genetic analyses, provide fine details of the molecular interactions associated with particle stability and membrane dynamics. The N- and C-termini of the major coat protein (P3), which are required for capsid assembly, act as conformational switches bridging capsid to membrane and linking P3 trimers. Electrostatic P3-membrane interactions increase virion stability upon DNA packaging. Newly revealed proteins suggest how the metastable vertex works and how the capsid edges are stabilized.
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The line below this paragraph, {{ABSTRACT_PUBMED_12219080}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12219080 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12219080}}
==About this Structure==
==About this Structure==
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[[Category: Tectiviridae]]
[[Category: Tectiviridae]]
[[Category: Virus/viral protein]]
[[Category: Virus/viral protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:05:19 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:12:15 2008''

Revision as of 03:12, 1 July 2008

Image:1gw7.png

Template:STRUCTURE 1gw7

QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 CAPSID, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY.

Template:ABSTRACT PUBMED 12219080

About this Structure

1GW7 is a Single protein structure of sequence from Enterobacteria phage prd1. Full crystallographic information is available from OCA.

Reference

Minor proteins, mobile arms and membrane-capsid interactions in the bacteriophage PRD1 capsid., San Martin C, Huiskonen JT, Bamford JK, Butcher SJ, Fuller SD, Bamford DH, Burnett RM, Nat Struct Biol. 2002 Oct;9(10):756-63. PMID:12219080

Page seeded by OCA on Tue Jul 1 06:12:15 2008

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