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1ho3

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[[Image:1ho3.gif|left|200px]]
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{{STRUCTURE_1ho3| PDB=1ho3 | SCENE= }}
{{STRUCTURE_1ho3| PDB=1ho3 | SCENE= }}
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'''CRYSTAL STRUCTURE ANALYSIS OF E. COLI L-ASPARAGINASE II (Y25F MUTANT)'''
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===CRYSTAL STRUCTURE ANALYSIS OF E. COLI L-ASPARAGINASE II (Y25F MUTANT)===
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==Overview==
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Quasi-enantiomorphic crystals of the Y25F mutant of Escherichia coli L-asparaginase and of the native Erwinia chrysanthemi L-asparaginase were obtained in the hexagonal space groups P6(5)22 and P6(1)22, respectively. The structures of these highly homologous enzymes were solved by molecular replacement and were refined with data extending to 2.2-2.5 A. These structures were compared with each other, as well as with other L-asparaginase structures previously observed with different crystal packing. It is concluded that the observed phenomenon, which is rare, was most likely to have arisen by chance.
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(as it appears on PubMed at http://www.pubmed.gov), where 11223513 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11223513}}
==About this Structure==
==About this Structure==
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[[Category: Asparaginase]]
[[Category: Asparaginase]]
[[Category: Leukemia]]
[[Category: Leukemia]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:03:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:27:28 2008''

Revision as of 05:27, 1 July 2008

Image:1ho3.png

Template:STRUCTURE 1ho3

CRYSTAL STRUCTURE ANALYSIS OF E. COLI L-ASPARAGINASE II (Y25F MUTANT)

Template:ABSTRACT PUBMED 11223513

About this Structure

1HO3 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structures of two highly homologous bacterial L-asparaginases: a case of enantiomorphic space groups., Jaskolski M, Kozak M, Lubkowski J, Palm G, Wlodawer A, Acta Crystallogr D Biol Crystallogr. 2001 Mar;57(Pt 3):369-77. PMID:11223513

Page seeded by OCA on Tue Jul 1 08:27:28 2008

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