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1kv9

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[[Image:1kv9.jpg|left|200px]]
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{{STRUCTURE_1kv9| PDB=1kv9 | SCENE= }}
{{STRUCTURE_1kv9| PDB=1kv9 | SCENE= }}
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'''Structure at 1.9 A Resolution of a Quinohemoprotein Alcohol Dehydrogenase from Pseudomonas putida HK5'''
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===Structure at 1.9 A Resolution of a Quinohemoprotein Alcohol Dehydrogenase from Pseudomonas putida HK5===
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==Overview==
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The type II quinohemoprotein alcohol dehydrogenase of Pseudomonas putida is a periplasmic enzyme that oxidizes substrate alcohols to the aldehyde and transfers electrons first to pyrroloquinoline quinone (PQQ) and then to an internal heme group. The 1.9 A resolution crystal structure reveals that the enzyme contains a large N-terminal eight-stranded beta propeller domain (approximately 60 kDa) similar to methanol dehydrogenase and a small C-terminal c-type cytochrome domain (approximately 10 kDa) similar to the cytochrome subunit of p-cresol methylhydoxylase. The PQQ is bound near the axis of the propeller domain about 14 A from the heme. A molecule of acetone, the product of the oxidation of isopropanol present during crystallization, appears to be bound in the active site cavity.
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(as it appears on PubMed at http://www.pubmed.gov), where 12057198 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12057198}}
==About this Structure==
==About this Structure==
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[[Category: Electron transfer]]
[[Category: Electron transfer]]
[[Category: Quinohemoprotein alcohol dehydrogenase]]
[[Category: Quinohemoprotein alcohol dehydrogenase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 23:12:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 11:04:27 2008''

Revision as of 08:04, 2 July 2008

Image:1kv9.png

Template:STRUCTURE 1kv9

Structure at 1.9 A Resolution of a Quinohemoprotein Alcohol Dehydrogenase from Pseudomonas putida HK5

Template:ABSTRACT PUBMED 12057198

About this Structure

1KV9 is a Single protein structure of sequence from Pseudomonas putida. Full crystallographic information is available from OCA.

Reference

Structure at 1.9 A resolution of a quinohemoprotein alcohol dehydrogenase from Pseudomonas putida HK5., Chen ZW, Matsushita K, Yamashita T, Fujii TA, Toyama H, Adachi O, Bellamy HD, Mathews FS, Structure. 2002 Jun;10(6):837-49. PMID:12057198

Page seeded by OCA on Wed Jul 2 11:04:27 2008

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