1mee

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[[Image:1mee.gif|left|200px]]
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{{STRUCTURE_1mee| PDB=1mee | SCENE= }}
{{STRUCTURE_1mee| PDB=1mee | SCENE= }}
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'''THE COMPLEX BETWEEN THE SUBTILISIN FROM A MESOPHILIC BACTERIUM AND THE LEECH INHIBITOR EGLIN-C'''
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===THE COMPLEX BETWEEN THE SUBTILISIN FROM A MESOPHILIC BACTERIUM AND THE LEECH INHIBITOR EGLIN-C===
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==Overview==
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The alkaline proteinase from the mesophilic bacterium Bacillus mesentericus has been crystallized in a 1:1 complex with the inhibitor eglin-C from the medical leech. The crystals have cell dimensions of a = 43.0, b = 71.9, c = 48.3 A and beta = 110.0 degrees and are in the space group P2(1). Three-dimensional data to 2.0 A have been recorded on film from a single crystal. The orientation and position of the complex in the unit cell have been established using the refined coordinates of subtilisin Carlsberg and of eglin-C as independent models. The structure of the complex has been refined by restrained least-squares minimization. The crystallographic R factor (= sigma[magnitude of Fo - magnitude of Fc[/sigma magnitude of Fo) is 15.1% including two Ca2+ ions and 312 water molecules. The structure is discussed in terms of its physicochemical properties in solution and its relation to other Bacillus subtilisins.
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(as it appears on PubMed at http://www.pubmed.gov), where 1793542 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1793542}}
==About this Structure==
==About this Structure==
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[[Category: Dauter, Z.]]
[[Category: Dauter, Z.]]
[[Category: Wilson, K S.]]
[[Category: Wilson, K S.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:56:25 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:47:34 2008''

Revision as of 20:47, 2 July 2008

Image:1mee.png

Template:STRUCTURE 1mee

THE COMPLEX BETWEEN THE SUBTILISIN FROM A MESOPHILIC BACTERIUM AND THE LEECH INHIBITOR EGLIN-C

Template:ABSTRACT PUBMED 1793542

About this Structure

1MEE is a Protein complex structure of sequences from Bacillus pumilus and Hirudo medicinalis. Full crystallographic information is available from OCA.

Reference

Complex between the subtilisin from a mesophilic bacterium and the leech inhibitor eglin-C., Dauter Z, Betzel C, Genov N, Pipon N, Wilson KS, Acta Crystallogr B. 1991 Oct 1;47 ( Pt 5):707-30. PMID:1793542

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