This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2qf4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2qf4.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2qf4.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2qf4| PDB=2qf4 | SCENE= }}
{{STRUCTURE_2qf4| PDB=2qf4 | SCENE= }}
-
'''High resolution structure of the major periplasmic domain from the cell shape-determining filament MreC (orthorhombic form)'''
+
===High resolution structure of the major periplasmic domain from the cell shape-determining filament MreC (orthorhombic form)===
-
==Overview==
+
<!--
-
Bacterial cell shape is dictated by the cell wall, a plastic structure that must adapt to growth and division whilst retaining its function as a selectively permeable barrier. The modulation of cell wall structure is achieved by a variety of enzymatic functions, all of which must be spatially regulated in a precise manner. The membrane-spanning essential protein MreC has been identified as the central hub in this process, linking the bacterial cytoskeleton to a variety of cell wall-modifying enzymes. Additionally, MreC can form filaments, believed to run perpendicularly to the membrane. We present here the 1.2 A resolution crystal structure of the major periplasmic domain of Streptococcus pneumoniae MreC. The protein shows a novel arrangement of two barrel-shaped domains, one of which shows homology to a known protein oligomerization motif, with the other resembling a catalytic domain from a bacterial protease. We discuss the implications of these results for MreC function, and detail the structural features of the molecule that may be responsible for the binding of partner proteins.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17707860}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17707860 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17707860}}
==About this Structure==
==About this Structure==
Line 26: Line 30:
[[Category: Filament a-lytic protease fold]]
[[Category: Filament a-lytic protease fold]]
[[Category: Structural protein]]
[[Category: Structural protein]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 14:51:04 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 12:39:10 2008''

Revision as of 09:39, 27 July 2008

Image:2qf4.png

Template:STRUCTURE 2qf4

High resolution structure of the major periplasmic domain from the cell shape-determining filament MreC (orthorhombic form)

Template:ABSTRACT PUBMED 17707860

About this Structure

2QF4 is a Single protein structure of sequence from Streptococcus pneumoniae r6. Full crystallographic information is available from OCA.

Reference

High-resolution structure of the major periplasmic domain from the cell shape-determining filament MreC., Lovering AL, Strynadka NC, J Mol Biol. 2007 Sep 28;372(4):1034-44. Epub 2007 Jul 26. PMID:17707860

Page seeded by OCA on Sun Jul 27 12:39:10 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2qf4"
Personal tools