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2c1d

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{{STRUCTURE_2c1d| PDB=2c1d | SCENE= }}
{{STRUCTURE_2c1d| PDB=2c1d | SCENE= }}
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'''CRYSTAL STRUCTURE OF SOXXA FROM P. PANTOTROPHUS'''
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===CRYSTAL STRUCTURE OF SOXXA FROM P. PANTOTROPHUS===
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==Overview==
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The sulfur-oxidizing enzyme system (Sox) of the chemotroph Paracoccus pantotrophus is composed of several proteins, which together oxidize hydrogen sulfide, sulfur, thiosulfate or sulfite and transfers the gained electrons to the respiratory chain. The hetero-dimeric cytochrome c complex SoxXA functions as heme enzyme and links covalently the sulfur substrate to the thiol of the cysteine-138 residue of the SoxY protein of the SoxYZ complex. Here, we report the crystal structure of the c-type cytochrome complex SoxXA. The structure could be solved by molecular replacement and refined to a resolution of 1.9A identifying the axial heme-iron coordination involving an unusual Cys-251 thiolate of heme2. Distance measurements between the three heme groups provide deeper insight into the electron transport inside SoxXA and merge in a better understanding of the initial step of the aerobic sulfur oxidation process in chemotrophic bacteria.
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(as it appears on PubMed at http://www.pubmed.gov), where 16297640 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16297640}}
==About this Structure==
==About this Structure==
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Sulfur oxidation]]
[[Category: Sulfur oxidation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 21:05:38 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:23:07 2008''

Revision as of 12:23, 27 July 2008

Image:2c1d.png

Template:STRUCTURE 2c1d

CRYSTAL STRUCTURE OF SOXXA FROM P. PANTOTROPHUS

Template:ABSTRACT PUBMED 16297640

About this Structure

2C1D is a Protein complex structure of sequences from Paracoccus denitrificans and Paracoccus pantotrophus. Full crystallographic information is available from OCA.

Reference

Structure of the cytochrome complex SoxXA of Paracoccus pantotrophus, a heme enzyme initiating chemotrophic sulfur oxidation., Dambe T, Quentmeier A, Rother D, Friedrich C, Scheidig AJ, J Struct Biol. 2005 Dec;152(3):229-34. Epub 2005 Nov 2. PMID:16297640

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