1w9a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1w9a.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1w9a.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1w9a| PDB=1w9a | SCENE= }}
{{STRUCTURE_1w9a| PDB=1w9a | SCENE= }}
-
'''CRYSTAL STRUCTURE OF RV1155 FROM MYCOBACTERIUM TUBERCULOSIS'''
+
===CRYSTAL STRUCTURE OF RV1155 FROM MYCOBACTERIUM TUBERCULOSIS===
-
==Overview==
+
<!--
-
With the aim of elucidating the biological function of hypothetical proteins unique amongst the Actynomyces sub-group of bacteria, we have solved the crystal structure of the conserved hypothetical protein Rv1155 from Mycobacterium tuberculosis at 1.8 A resolution. Rv1155 is a homodimer both in the crystal structure and in solution and folds into two separate domains consisting of a six-stranded anti-parallel beta-barrel fold flanked by two alpha-helices and a helix-turn-helix domain. Both domains contribute to the formation of two deep clefts at the dimer interface. The overall fold of Rv1155 strikingly resembles that of flavin mononucleotide-binding protein and pyridoxamine 5'-phosphate oxydase, but the architecture of the putative binding pocket is markedly different, consistent with the lack of color of Rv1155 and its inability to bind FMN. Rv1155 thus appears to belong to a group of proteins with stringent conservation of the binding cleft, having evolved towards a new binding function.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15620716}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15620716 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15620716}}
==About this Structure==
==About this Structure==
Line 34: Line 38:
[[Category: Related to fmn-binding protein]]
[[Category: Related to fmn-binding protein]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 13:20:09 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:39:49 2008''

Revision as of 12:39, 27 July 2008

Image:1w9a.png

Template:STRUCTURE 1w9a

CRYSTAL STRUCTURE OF RV1155 FROM MYCOBACTERIUM TUBERCULOSIS

Template:ABSTRACT PUBMED 15620716

About this Structure

1W9A is a Single protein structure of sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

Crystal structure of the conserved hypothetical protein Rv1155 from Mycobacterium tuberculosis., Canaan S, Sulzenbacher G, Roig-Zamboni V, Scappuccini-Calvo L, Frassinetti F, Maurin D, Cambillau C, Bourne Y, FEBS Lett. 2005 Jan 3;579(1):215-21. PMID:15620716

Page seeded by OCA on Sun Jul 27 15:39:49 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1w9a"
Personal tools