This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1s0u

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1s0u.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1s0u.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1s0u| PDB=1s0u | SCENE= }}
{{STRUCTURE_1s0u| PDB=1s0u | SCENE= }}
-
'''eIF2gamma apo'''
+
===eIF2gamma apo===
-
==Overview==
+
<!--
-
The x-ray structure of the gamma-subunit of the heterotrimeric translation initiation factor eIF2 has been determined to 2.4-A resolution. eIF2 is a GTPase that delivers the initiator Met-tRNA to the P site on the small ribosomal subunit during a rate-limiting initiation step in translation. The structure of eIF2gamma closely resembles that of EF1A.GTP, consisting of an N-terminal G domain followed by two beta-barrels arranged in a closed configuration with domain II packed against the G domain in the vicinity of the Switch regions. The G domain of eIF2gamma has an unusual zinc ribbon motif, not previously found in other GTPases. Structure-based site-directed mutagenesis was used to identify two adjacent features on the surface of eIF2gamma that bind the alpha-subunit and Met-tRNA(i)(Met), respectively. These structural, biochemical, and genetic results provide new insights into eIF2 ternary complex assembly.
+
The line below this paragraph, {{ABSTRACT_PUBMED_14688270}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 14688270 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_14688270}}
==About this Structure==
==About this Structure==
Line 32: Line 36:
[[Category: Translation initiation]]
[[Category: Translation initiation]]
[[Category: Trna]]
[[Category: Trna]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:09:14 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:43:34 2008''

Revision as of 15:43, 27 July 2008

Image:1s0u.png

Template:STRUCTURE 1s0u

eIF2gamma apo

Template:ABSTRACT PUBMED 14688270

About this Structure

1S0U is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.

Reference

X-ray structure of translation initiation factor eIF2gamma: implications for tRNA and eIF2alpha binding., Roll-Mecak A, Alone P, Cao C, Dever TE, Burley SK, J Biol Chem. 2004 Mar 12;279(11):10634-42. Epub 2003 Dec 19. PMID:14688270

Page seeded by OCA on Sun Jul 27 18:43:34 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1s0u"
Personal tools