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2hnx

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[[Image:2hnx.gif|left|200px]]
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[[Image:2hnx.png|left|200px]]
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{{STRUCTURE_2hnx| PDB=2hnx | SCENE= }}
{{STRUCTURE_2hnx| PDB=2hnx | SCENE= }}
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'''Crystal Structure of aP2'''
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===Crystal Structure of aP2===
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==Overview==
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Human adipocyte lipid-binding protein (aP2) belongs to a family of intracellular lipid-binding proteins involved in the transport and storage of lipids. Here, the crystal structure of human aP2 with a bound palmitate is described at 1.5 A resolution. Unlike the known crystal structure of murine aP2 in complex with palmitate, this structure shows that the fatty acid is in a folded conformation and that the loop containing Phe57 acts as a lid to regulate ligand binding by excluding solvent exposure to the central binding cavity.
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(as it appears on PubMed at http://www.pubmed.gov), where 17077479 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17077479}}
==About this Structure==
==About this Structure==
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[[Category: Tardie, M.]]
[[Category: Tardie, M.]]
[[Category: Fatty acid binding protein]]
[[Category: Fatty acid binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:29:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:13:07 2008''

Revision as of 16:13, 27 July 2008

Image:2hnx.png

Template:STRUCTURE 2hnx

Crystal Structure of aP2

Template:ABSTRACT PUBMED 17077479

About this Structure

2HNX is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Expression, purification, crystallization and structure of human adipocyte lipid-binding protein (aP2)., Marr E, Tardie M, Carty M, Brown Phillips T, Wang IK, Soeller W, Qiu X, Karam G, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Nov 1;62(Pt, 11):1058-60. Epub 2006 Oct 25. PMID:17077479

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