This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1xbi

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1xbi.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1xbi.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1xbi| PDB=1xbi | SCENE= }}
{{STRUCTURE_1xbi| PDB=1xbi | SCENE= }}
-
'''High resolution structure of Methanocaldococcus jannaschii L7AE'''
+
===High resolution structure of Methanocaldococcus jannaschii L7AE===
-
==Overview==
+
<!--
-
Archaeal ribosomal protein L7Ae is a multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal, box H/ACA, and box C/D sRNAs. The crystal structure of Methanocaldococcus jannaschii L7Ae has been determined to 1.45 A, and L7Ae's amino acid composition, evolutionary conservation, functional characteristics, and structural details have been analyzed. Comparison of the L7Ae structure to those of a number of related proteins with diverse functions has revealed significant structural homology which suggests that this protein fold is an ancient RNA-binding motif. Notably, the free M. jannaschii L7Ae structure is essentially identical to that with RNA bound, suggesting that RNA binding occurs through an induced-fit interaction. Circular dichroism experiments show that box C/D and C'/D' RNA motifs undergo conformational changes when magnesium or the L7Ae protein is added, corroborating the induced-fit model for L7Ae-box C/D RNA interactions.
+
The line below this paragraph, {{ABSTRACT_PUBMED_16008351}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 16008351 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_16008351}}
==About this Structure==
==About this Structure==
Line 28: Line 32:
[[Category: Tran, E J.]]
[[Category: Tran, E J.]]
[[Category: Alpha-beta-alpha sandwich fold]]
[[Category: Alpha-beta-alpha sandwich fold]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 14:49:22 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:22:12 2008''

Revision as of 17:22, 27 July 2008

Image:1xbi.png

Template:STRUCTURE 1xbi

High resolution structure of Methanocaldococcus jannaschii L7AE

Template:ABSTRACT PUBMED 16008351

About this Structure

1XBI is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.

Reference

The crystal structure of the Methanocaldococcus jannaschii multifunctional L7Ae RNA-binding protein reveals an induced-fit interaction with the box C/D RNAs., Suryadi J, Tran EJ, Maxwell ES, Brown BA 2nd, Biochemistry. 2005 Jul 19;44(28):9657-72. PMID:16008351

Page seeded by OCA on Sun Jul 27 20:22:12 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1xbi"
Personal tools