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2aoz

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[[Image:2aoz.gif|left|200px]]
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{{STRUCTURE_2aoz| PDB=2aoz | SCENE= }}
{{STRUCTURE_2aoz| PDB=2aoz | SCENE= }}
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'''Crystal structure of the myotoxin-II from Atropoides nummifer venom'''
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===Crystal structure of the myotoxin-II from Atropoides nummifer venom===
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==Overview==
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Lys49 snake-venom phospholipase A2 (PLA2) homologues are highly myotoxic proteins which, although lacking catalytic activity, possess the ability to disrupt biological membranes, inducing significant muscle-tissue loss and permanent disability in severely envenomed patients. Since the structural basis for their toxic activity is still only partially understood, the structure of myotoxin II, a monomeric Lys49 PLA2 homologue from Atropoides nummifer, has been determined at 2.08 angstroms resolution and the anion-binding site has been characterized.
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(as it appears on PubMed at http://www.pubmed.gov), where 16682766 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16682766}}
==About this Structure==
==About this Structure==
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[[Category: Phospholipase a2]]
[[Category: Phospholipase a2]]
[[Category: X-ray diffration]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 19:18:14 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:32:19 2008''

Revision as of 20:32, 27 July 2008

Image:2aoz.png

Template:STRUCTURE 2aoz

Crystal structure of the myotoxin-II from Atropoides nummifer venom

Template:ABSTRACT PUBMED 16682766

About this Structure

2AOZ is a Single protein structure of sequence from Atropoides nummifer. Full crystallographic information is available from OCA.

Reference

Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom., Murakami MT, Melo CC, Angulo Y, Lomonte B, Arni RK, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):423-6. Epub 2006 Apr 12. PMID:16682766

Page seeded by OCA on Sun Jul 27 23:32:19 2008

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