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2j00

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{{STRUCTURE_2j00| PDB=2j00 | SCENE= }}
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'''STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 1 OF 4). THIS FILE CONTAINS THE 30S SUBUNIT, MRNA, A-, P- AND E-SITE TRNAS AND PAROMOMYCIN FOR MOLECULE I.'''
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===STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 1 OF 4). THIS FILE CONTAINS THE 30S SUBUNIT, MRNA, A-, P- AND E-SITE TRNAS AND PAROMOMYCIN FOR MOLECULE I.===
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==Overview==
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The crystal structure of the bacterial 70S ribosome refined to 2.8 angstrom resolution reveals atomic details of its interactions with messenger RNA (mRNA) and transfer RNA (tRNA). A metal ion stabilizes a kink in the mRNA that demarcates the boundary between A and P sites, which is potentially important to prevent slippage of mRNA. Metal ions also stabilize the intersubunit interface. The interactions of E-site tRNA with the 50S subunit have both similarities and differences compared to those in the archaeal ribosome. The structure also rationalizes much biochemical and genetic data on translation.
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The line below this paragraph, {{ABSTRACT_PUBMED_16959973}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16959973 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16959973}}
==About this Structure==
==About this Structure==
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[[Category: Translation]]
[[Category: Translation]]
[[Category: Trna]]
[[Category: Trna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 08:08:40 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 02:30:51 2008''

Revision as of 23:30, 27 July 2008

Image:2j00.png

Template:STRUCTURE 2j00

STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 1 OF 4). THIS FILE CONTAINS THE 30S SUBUNIT, MRNA, A-, P- AND E-SITE TRNAS AND PAROMOMYCIN FOR MOLECULE I.

Template:ABSTRACT PUBMED 16959973

About this Structure

2J00 is a Protein complex structure of sequences from Escherichia coli and Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

Structure of the 70S ribosome complexed with mRNA and tRNA., Selmer M, Dunham CM, Murphy FV 4th, Weixlbaumer A, Petry S, Kelley AC, Weir JR, Ramakrishnan V, Science. 2006 Sep 29;313(5795):1935-42. Epub 2006 Sep 7. PMID:16959973

Page seeded by OCA on Mon Jul 28 02:30:51 2008

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