1v7x

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1v7x.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1v7x.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1v7x| PDB=1v7x | SCENE= }}
{{STRUCTURE_1v7x| PDB=1v7x | SCENE= }}
-
'''Crystal structure of Vibrio proteolyticus chitobiose phosphorylase in complex with GlcNAc and sulfate'''
+
===Crystal structure of Vibrio proteolyticus chitobiose phosphorylase in complex with GlcNAc and sulfate===
-
==Overview==
+
<!--
-
Vibrio proteolyticus chitobiose phosphorylase (ChBP) belongs to glycosyl transferase family 36 (GT-36), and catalyzes the reversible phosphorolysis of chitobiose into alpha-GlcNAc-1-phosphate and GlcNAc with inversion of the anomeric configuration. As the first known structures of a GT-36 enzyme, we determined the crystal structure of ChBP in a ternary complex with GlcNAc and SO(4). It is also the first structures of an inverting phosphorolytic enzyme in a complex with a sugar and a sulfate ion, and reveals a pseudo-ternary complex structure of enzyme-sugar-phosphate. ChBP comprises a beta sandwich domain and an (alpha/alpha)(6) barrel domain, constituting a distinctive structure among GT families. Instead, it shows significant structural similarity with glycoside hydrolase (GH) enzymes, glucoamylases (GH-15), and maltose phosphorylase (GH-65) in clan GH-L. The structural similarity reported here, together with distant sequence similarities between ChBP and GHs, led to the reclassification of family GT-36 into a novel GH family, namely GH-94.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15274915}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15274915 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15274915}}
==About this Structure==
==About this Structure==
Line 31: Line 35:
[[Category: Wakagi, T.]]
[[Category: Wakagi, T.]]
[[Category: Beta-sandwich]]
[[Category: Beta-sandwich]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 12:11:38 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:30:12 2008''

Revision as of 02:30, 28 July 2008

Image:1v7x.png

Template:STRUCTURE 1v7x

Crystal structure of Vibrio proteolyticus chitobiose phosphorylase in complex with GlcNAc and sulfate

Template:ABSTRACT PUBMED 15274915

About this Structure

1V7X is a Single protein structure of sequence from Vibrio proteolyticus. Full crystallographic information is available from OCA.

Reference

Chitobiose phosphorylase from Vibrio proteolyticus, a member of glycosyl transferase family 36, has a clan GH-L-like (alpha/alpha)(6) barrel fold., Hidaka M, Honda Y, Kitaoka M, Nirasawa S, Hayashi K, Wakagi T, Shoun H, Fushinobu S, Structure. 2004 Jun;12(6):937-47. PMID:15274915

Page seeded by OCA on Mon Jul 28 05:30:12 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1v7x"
Personal tools