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1v96

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{{STRUCTURE_1v96| PDB=1v96 | SCENE= }}
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'''Crystal structure of hypothetical protein of unknown function from pyrococcus horikoshii OT3'''
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===Crystal structure of hypothetical protein of unknown function from pyrococcus horikoshii OT3===
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==Overview==
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The Pyrococcus horikoshii OT3 protein PH0500 is highly conserved within the Pyrococcus genus of hyperthermophilic archaea and shows low amino-acid sequence similarity with a family of PIN-domain proteins. The protein has been expressed, purified and crystallized in two crystal forms: PH0500-I and PH0500-II. The structure was determined at 2.0 A by the multiple anomalous dispersion method using a selenomethionyl derivative of crystal form PH0500-I (PH0500-I-Se). The structure of PH0500-I has been refined at 1.75 A resolution to an R factor of 20.9% and the structure of PH0500-II has been refined at 2.0 A resolution to an R factor of 23.4%. In both crystal forms as well as in solution the molecule appears to be a dimer. Searches of the databases for protein-fold similarities confirmed that the PH0500 protein is a PIN-domain protein with possible exonuclease activity and involvement in DNA or RNA editing.
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(as it appears on PubMed at http://www.pubmed.gov), where 16511069 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16511069}}
==About this Structure==
==About this Structure==
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Trna synthetase]]
[[Category: Trna synthetase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 12:14:58 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:57:03 2008''

Revision as of 04:57, 28 July 2008

Image:1v96.png

Template:STRUCTURE 1v96

Crystal structure of hypothetical protein of unknown function from pyrococcus horikoshii OT3

Template:ABSTRACT PUBMED 16511069

About this Structure

1V96 is a Single protein structure of sequence from Pyrococcus horikoshii. Full crystallographic information is available from OCA.

Reference

Structure of PIN-domain protein PH0500 from Pyrococcus horikoshii., Jeyakanthan J, Inagaki E, Kuroishi C, Tahirov TH, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 May 1;61(Pt, 5):463-8. Epub 2005 Apr 26. PMID:16511069

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