1nhy

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1nhy.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1nhy.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1nhy| PDB=1nhy | SCENE= }}
{{STRUCTURE_1nhy| PDB=1nhy | SCENE= }}
-
'''Crystal Structure of the GST-like Domain of Elongation Factor 1-gamma from Saccharomyces cerevisiae.'''
+
===Crystal Structure of the GST-like Domain of Elongation Factor 1-gamma from Saccharomyces cerevisiae.===
-
==Overview==
+
<!--
-
The crystal structure of the N-terminal 219 residues (domain 1) of the conserved eukaryotic translation elongation factor 1Bgamma (eEF1Bgamma), encoded by the TEF3 gene in Saccharomyces cerevisiae, has been determined at 3.0 A resolution by the single wavelength anomalous dispersion technique. The structure is overall very similar to the glutathione S-transferase proteins and contains a pocket with architecture highly homologous to what is observed in glutathione S-transferase enzymes. The TEF3-encoded form of eEF1Bgamma has no obvious catalytic residue. However, the second form of eEF1Bgamma encoded by the TEF4 gene contains serine 11, which may act catalytically. Based on the x-ray structure and gel filtration studies, we suggest that the yeast eEF1 complex is organized as an [eEF1A.eEF1Balpha.eEF1Bgamma]2 complex. A 23-residue sequence in the middle of eEF1Bgamma is essential for the stable dimerization of eEF1Bgamma and the quaternary structure of the eEF1 complex.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12972429}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12972429 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12972429}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Gst-like]]
[[Category: Gst-like]]
[[Category: Protein synthesis]]
[[Category: Protein synthesis]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:33:07 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:49:08 2008''

Revision as of 08:49, 28 July 2008

Image:1nhy.png

Template:STRUCTURE 1nhy

Crystal Structure of the GST-like Domain of Elongation Factor 1-gamma from Saccharomyces cerevisiae.

Template:ABSTRACT PUBMED 12972429

About this Structure

1NHY is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

The crystal structure of the glutathione S-transferase-like domain of elongation factor 1Bgamma from Saccharomyces cerevisiae., Jeppesen MG, Ortiz P, Shepard W, Kinzy TG, Nyborg J, Andersen GR, J Biol Chem. 2003 Nov 21;278(47):47190-8. Epub 2003 Sep 12. PMID:12972429

Page seeded by OCA on Mon Jul 28 11:49:08 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1nhy"
Personal tools