2cw3

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[[Image:2cw3.gif|left|200px]]
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{{Seed}}
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[[Image:2cw3.png|left|200px]]
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{{STRUCTURE_2cw3| PDB=2cw3 | SCENE= }}
{{STRUCTURE_2cw3| PDB=2cw3 | SCENE= }}
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'''X-ray structure of PmSOD2, superoxide dismutase from Perkinsus marinus'''
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===X-ray structure of PmSOD2, superoxide dismutase from Perkinsus marinus===
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==Overview==
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Perkinsus marinus, a facultative intracellular parasite of the eastern oyster Crassostrea virginica, is responsible for mass mortalities of oyster populations. P. marinus trophozoites survive and proliferate within oyster hemocytes, invading most tissues and fluids, thus causing a systemic infection that eventually kills the host. The phagocytosis of P. marinus trophozoites lacks a respiratory burst, suggesting that the parasite has mechanisms that actively abrogate the host's oxidative defense responses. One mechanism and the first line of defense against oxidative damage is the dismutation of superoxide radical to molecular oxygen and hydrogen peroxide by superoxide dismutases (SODs). P. marinus possesses two iron-cofactored SODs, PmSOD1 and PmSOD2. Here, the crystallization and X-ray structures of both PmSOD1 and PmSOD2 are presented.
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(as it appears on PubMed at http://www.pubmed.gov), where 17077482 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17077482}}
==About this Structure==
==About this Structure==
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[[Category: Vasta, G R.]]
[[Category: Vasta, G R.]]
[[Category: Sod]]
[[Category: Sod]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 23:11:17 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:29:52 2008''

Revision as of 11:29, 28 July 2008

Image:2cw3.png

Template:STRUCTURE 2cw3

X-ray structure of PmSOD2, superoxide dismutase from Perkinsus marinus

Template:ABSTRACT PUBMED 17077482

About this Structure

2CW3 is a Single protein structure of sequence from Perkinsus marinus. Full crystallographic information is available from OCA.

Reference

Structures of PmSOD1 and PmSOD2, two superoxide dismutases from the protozoan parasite Perkinsus marinus., Asojo OA, Schott EJ, Vasta GR, Silva AM, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Nov 1;62(Pt, 11):1072-5. Epub 2006 Oct 25. PMID:17077482

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