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1n4y

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[[Image:1n4y.gif|left|200px]]
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{{STRUCTURE_1n4y| PDB=1n4y | SCENE= }}
{{STRUCTURE_1n4y| PDB=1n4y | SCENE= }}
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'''REFINED STRUCTURE OF KISTRIN'''
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===REFINED STRUCTURE OF KISTRIN===
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==Overview==
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The structure of kistrin, which is a member of a homologous family of glycoprotein IIb-IIIa (GP IIb-IIIa) antagonists and potent protein inhibitors of platelet aggregation, has been determined by two-dimensional nuclear magnetic resonance (NMR) spectroscopy. The 68-residue protein consists of a series of tightly packed loops held together by six disulfide bonds and has almost no regular secondary structure. Kistrin has an Arg-Gly-Asp (RGD) adhesion site recognition sequence important for binding to GP IIb-IIIa that is located at the apex of a long loop across the surface of the protein.
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The line below this paragraph, {{ABSTRACT_PUBMED_1862345}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 1862345 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1862345}}
==About this Structure==
==About this Structure==
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1N4Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1kst 1kst]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N4Y OCA].
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1N4Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1kst 1kst]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N4Y OCA].
==Reference==
==Reference==
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[[Category: Rgd]]
[[Category: Rgd]]
[[Category: Venom]]
[[Category: Venom]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:06:09 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 21:24:07 2008''

Revision as of 18:24, 28 July 2008

Image:1n4y.png

Template:STRUCTURE 1n4y

REFINED STRUCTURE OF KISTRIN

Template:ABSTRACT PUBMED 1862345

About this Structure

1N4Y is a Single protein structure of sequence from Calloselasma rhodostoma. This structure supersedes the now removed PDB entry 1kst. Full experimental information is available from OCA.

Reference

Solution structure of kistrin, a potent platelet aggregation inhibitor and GP IIb-IIIa antagonist., Adler M, Lazarus RA, Dennis MS, Wagner G, Science. 1991 Jul 26;253(5018):445-8. PMID:1862345

Page seeded by OCA on Mon Jul 28 21:24:07 2008

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