This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1s4r

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1s4r.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1s4r.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1s4r| PDB=1s4r | SCENE= }}
{{STRUCTURE_1s4r| PDB=1s4r | SCENE= }}
-
'''Structure of a reaction intermediate in the photocycle of PYP extracted by a SVD-driven analysis'''
+
===Structure of a reaction intermediate in the photocycle of PYP extracted by a SVD-driven analysis===
-
==Overview==
+
<!--
-
We determine the number of authentic reaction intermediates in the later stages of the photocycle of photoactive yellow protein at room temperature, their atomic structures, and a consistent set of chemical kinetic mechanisms, by analysis of a set of time-dependent difference electron density maps spanning the time range from 5 micros to 100 ms. The successful fit of exponentials to right singular vectors derived from a singular value decomposition of the difference maps demonstrates that a chemical kinetic mechanism holds and that structurally distinct intermediates exist. We identify two time-independent difference maps, from which we refine the structures of the corresponding intermediates. We thus demonstrate how structures associated with intermediate states can be extracted from the experimental, time-dependent crystallographic data. Stoichiometric and structural constraints allow the exclusion of one kinetic mechanism proposed for the photocycle but retain other plausible candidate kinetic mechanisms.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15041745}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15041745 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15041745}}
==About this Structure==
==About this Structure==
Line 31: Line 35:
[[Category: Srajer, V.]]
[[Category: Srajer, V.]]
[[Category: Reaction intermediate]]
[[Category: Reaction intermediate]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:17:51 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:18:52 2008''

Revision as of 12:18, 29 July 2008

Image:1s4r.png

Template:STRUCTURE 1s4r

Structure of a reaction intermediate in the photocycle of PYP extracted by a SVD-driven analysis

Template:ABSTRACT PUBMED 15041745

About this Structure

1S4R is a Single protein structure of sequence from Halorhodospira halophila. Full crystallographic information is available from OCA.

Reference

Protein kinetics: structures of intermediates and reaction mechanism from time-resolved x-ray data., Schmidt M, Pahl R, Srajer V, Anderson S, Ren Z, Ihee H, Rajagopal S, Moffat K, Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4799-804. Epub 2004 Mar 23. PMID:15041745

Page seeded by OCA on Tue Jul 29 15:18:52 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1s4r"
Personal tools