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3dg8

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(New page: '''Unreleased structure''' The entry 3dg8 is ON HOLD until Paper Publication Authors: Dasgupta, T., Chitnumsub, P., Maneeruttanarungroj, C., Kamchonwongpaisan, S., Nichols, S., Lyons, T...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3dg8.jpg|left|200px]]
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The entry 3dg8 is ON HOLD until Paper Publication
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{{STRUCTURE_3dg8| PDB=3dg8 | SCENE= }}
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Authors: Dasgupta, T., Chitnumsub, P., Maneeruttanarungroj, C., Kamchonwongpaisan, S., Nichols, S., Lyons, T.M., Tirado-Rives, J., Jorgensen, W.L., Yuthavong, Y., Anderson, K.S.
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===Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with RJF670, NADPH, and dUMP===
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Description: Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with RJF670, NADPH, and dUMP
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Jul 11 13:07:16 2008''
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{{ABSTRACT_PUBMED_19146480}}
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==About this Structure==
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3DG8 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DG8 OCA].
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==Reference==
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<ref group="xtra">PMID:19146480</ref><references group="xtra"/>
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[[Category: Plasmodium falciparum]]
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[[Category: Anderson, K S.]]
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[[Category: Chitnumsub, P.]]
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[[Category: Dasgupta, T.]]
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[[Category: Jorgensen, W L.]]
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[[Category: Kamchonwongpaisan, S.]]
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[[Category: Lyons, T M.]]
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[[Category: Maneeruttanarungroj, C.]]
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[[Category: Nichols, S.]]
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[[Category: Tirado-Rives, J.]]
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[[Category: Yuthavong, Y.]]
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[[Category: Alpha-beta]]
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[[Category: Methyltransferase]]
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[[Category: Oxidoreductase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 28 09:48:23 2009''

Revision as of 07:48, 28 January 2009

Template:STRUCTURE 3dg8

Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with RJF670, NADPH, and dUMP

Template:ABSTRACT PUBMED 19146480

About this Structure

3DG8 is a 4 chains structure of sequences from Plasmodium falciparum. Full crystallographic information is available from OCA.

Reference

  • Dasgupta T, Chitnumsub P, Kamchonwongpaisan S, Maneeruttanarungroj C, Nichols SE, Lyons TM, Tirado-Rives J, Jorgensen WL, Yuthavong Y, Anderson KS. Exploiting structural analysis, in silico screening, and serendipity to identify novel inhibitors of drug-resistant falciparum malaria. ACS Chem Biol. 2009 Jan 16;4(1):29-40. PMID:19146480 doi:10.1021/cb8002804

Page seeded by OCA on Wed Jan 28 09:48:23 2009

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