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3faa

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3faa.jpg|left|200px]]
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The entry 3faa is ON HOLD until Paper Publication
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{{STRUCTURE_3faa| PDB=3faa | SCENE= }}
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Authors: Boriack-Sjodin, P.A., Fitch, C.
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===Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor===
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Description: Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 14:40:08 2008''
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The line below this paragraph, {{ABSTRACT_PUBMED_19135364}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 19135364 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19135364}}
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==Disease==
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Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]], Loeys-Dietz syndrome, type 2A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]]
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==About this Structure==
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3FAA is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAA OCA].
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==Reference==
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<ref group="xtra">PMID:19135364</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Receptor protein serine/threonine kinase]]
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[[Category: Boriack-Sjodin, P A.]]
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[[Category: Fitch, C.]]
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[[Category: Atp-binding]]
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[[Category: Craniosynostosis]]
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[[Category: Disease mutation]]
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[[Category: Glycoprotein]]
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[[Category: Kinase]]
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[[Category: Magnesium]]
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[[Category: Manganese]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Protein-inhibitor complex]]
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[[Category: Receptor]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Structure-based drug design]]
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[[Category: Tgfbeta]]
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[[Category: Transferase]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 28 09:55:14 2009''

Revision as of 07:55, 28 January 2009

Image:3faa.jpg

Template:STRUCTURE 3faa

Contents

Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor

Template:ABSTRACT PUBMED 19135364

Disease

Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]

About this Structure

3FAA is a 5 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bonafoux D, Chuaqui C, Boriack-Sjodin PA, Fitch C, Hankins G, Josiah S, Black C, Hetu G, Ling L, Lee WC. 2-Aminoimidazoles inhibitors of TGF-beta receptor 1. Bioorg Med Chem Lett. 2009 Feb 1;19(3):912-6. Epub 2008 Dec 11. PMID:19135364 doi:10.1016/j.bmcl.2008.11.119

Page seeded by OCA on Wed Jan 28 09:55:14 2009

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