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1o4x

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==About this Structure==
==About this Structure==
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1O4X is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4X OCA].
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1O4X is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4X OCA].
==Reference==
==Reference==
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Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex., Williams DC Jr, Cai M, Clore GM, J Biol Chem. 2004 Jan 9;279(2):1449-57. Epub 2003 Oct 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14559893 14559893]
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<ref group="xtra">PMID:14559893</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Clore, G M.]]
[[Category: Clore, G M.]]
[[Category: Williams, D C.]]
[[Category: Williams, D C.]]
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[[Category: Transcription factor]]
[[Category: Transcription factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:56:27 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:07:11 2009''

Revision as of 13:07, 16 February 2009

Image:1o4x.png

Template:STRUCTURE 1o4x

Contents

TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT

Template:ABSTRACT PUBMED 14559893

Disease

Known disease associated with this structure: Microphthalmia, syndromic 3 OMIM:[184429], Optic nerve hypoplasia and abnormalities of the central nervous system OMIM:[184429]

About this Structure

1O4X is a 4 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Williams DC Jr, Cai M, Clore GM. Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex. J Biol Chem. 2004 Jan 9;279(2):1449-57. Epub 2003 Oct 14. PMID:14559893 doi:http://dx.doi.org/10.1074/jbc.M309790200

Page seeded by OCA on Mon Feb 16 15:07:11 2009

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