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3cyx
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
| - | 3CYX is a | + | 3CYX is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CYX OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:18597780</ref><ref group="xtra">PMID:16962136</ref><ref group="xtra">PMID:16277992</ref><references group="xtra"/> | |
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[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Liu, F.]] | [[Category: Liu, F.]] | ||
[[Category: Weber, I T.]] | [[Category: Weber, I T.]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:57:37 2009'' |
Revision as of 03:57, 17 February 2009
Crystal structure of HIV-1 mutant I50V and inhibitor saquinavira
Template:ABSTRACT PUBMED 18597780
About this Structure
3CYX is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Liu F, Kovalevsky AY, Tie Y, Ghosh AK, Harrison RW, Weber IT. Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. J Mol Biol. 2008 Aug 1;381(1):102-15. Epub 2008 Jul 1. PMID:18597780 doi:10.1016/j.jmb.2008.05.062
- Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114. J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:16962136 doi:10.1016/j.jmb.2006.08.007
- Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT. Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J Mol Biol. 2005 Dec 9;354(4):789-800. Epub 2005 Oct 21. PMID:16277992 doi:10.1016/j.jmb.2005.09.095
Page seeded by OCA on Tue Feb 17 05:57:37 2009
