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1tmj
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
| - | 1TMJ is a | + | 1TMJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TMJ OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:15952765</ref><ref group="xtra">PMID:10378268</ref><ref group="xtra">PMID:11080626</ref><ref group="xtra">PMID:11311059</ref><references group="xtra"/> | |
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[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]] | [[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Blaszczyk, J.]] | [[Category: Blaszczyk, J.]] | ||
[[Category: Ji, X.]] | [[Category: Ji, X.]] | ||
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[[Category: X-ray crystallography]] | [[Category: X-ray crystallography]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:15:11 2009'' |
Revision as of 06:15, 17 February 2009
Crystal structure of E.coli apo-HPPK(W89A) at 1.45 Angstrom resolution
Template:ABSTRACT PUBMED 15952765
About this Structure
1TMJ is a 1 chain structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Li Y, Blaszczyk J, Wu Y, Shi G, Ji X, Yan H. Is the critical role of loop 3 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase in catalysis due to loop-3 residues arginine-84 and tryptophan-89? Site-directed mutagenesis, biochemical, and crystallographic studies. Biochemistry. 2005 Jun 21;44(24):8590-9. PMID:15952765 doi:10.1021/bi0503495
- Xiao B, Shi G, Chen X, Yan H, Ji X. Crystal structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, a potential target for the development of novel antimicrobial agents. Structure. 1999 May;7(5):489-96. PMID:10378268
- Blaszczyk J, Shi G, Yan H, Ji X. Catalytic center assembly of HPPK as revealed by the crystal structure of a ternary complex at 1.25 A resolution. Structure. 2000 Oct 15;8(10):1049-58. PMID:11080626
- Shi G, Blaszczyk J, Ji X, Yan H. Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies. J Med Chem. 2001 Apr 26;44(9):1364-71. PMID:11311059
Page seeded by OCA on Tue Feb 17 08:15:11 2009
Categories: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase | Escherichia coli | Blaszczyk, J. | Ji, X. | 6-hydroxymethyl-7,8-dihydropterin | 6-hydroxymethylpterin | Antimicrobial agent | Drug design | Folate | Hppk | Point mutant | Pyrophosphokinase | Pyrophosphoryl transfer | Structural mutagenesis | X-ray crystallography
