2np8

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{{ABSTRACT_PUBMED_17157005}}
{{ABSTRACT_PUBMED_17157005}}
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==Disease==
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Known disease associated with this structure: Colon cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603072 603072]]
==About this Structure==
==About this Structure==
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2NP8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NP8 OCA].
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2NP8 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NP8 OCA].
==Reference==
==Reference==
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Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors., Tari LW, Hoffman ID, Bensen DC, Hunter MJ, Nix J, Nelson KJ, McRee DE, Swanson RV, Bioorg Med Chem Lett. 2007 Feb 1;17(3):688-91. Epub 2006 Nov 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17157005 17157005]
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<ref group="xtra">PMID:17157005</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Single protein]]
 
[[Category: Bensen, D C.]]
[[Category: Bensen, D C.]]
[[Category: Hoffman, I D.]]
[[Category: Hoffman, I D.]]
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[[Category: Kinase inhibitor]]
[[Category: Kinase inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:53:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:48:53 2009''

Revision as of 15:48, 17 February 2009

Image:2np8.png

Template:STRUCTURE 2np8

Contents

Structural Basis for the Inhibition of Aurora A Kinase by a Novel Class of High Affinity Disubstituted Pyrimidine Inhibitors

Template:ABSTRACT PUBMED 17157005

Disease

Known disease associated with this structure: Colon cancer, susceptibility to OMIM:[603072]

About this Structure

2NP8 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Tari LW, Hoffman ID, Bensen DC, Hunter MJ, Nix J, Nelson KJ, McRee DE, Swanson RV. Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors. Bioorg Med Chem Lett. 2007 Feb 1;17(3):688-91. Epub 2006 Nov 2. PMID:17157005 doi:http://dx.doi.org/10.1016/j.bmcl.2006.10.086

Page seeded by OCA on Tue Feb 17 17:48:53 2009

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