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3bft

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==About this Structure==
==About this Structure==
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3BFT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BFT OCA].
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3BFT is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BFT OCA].
==Reference==
==Reference==
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Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency., Beich-Frandsen M, Pickering DS, Mirza O, Johansen TN, Greenwood J, Vestergaard B, Schousboe A, Gajhede M, Liljefors T, Kastrup JS, J Med Chem. 2008 Mar 13;51(5):1459-63. Epub 2008 Feb 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18269227 18269227]
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<ref group="xtra">PMID:18269227</ref><ref group="xtra">PMID:11086992</ref><references group="xtra"/>
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Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core., Armstrong N, Gouaux E, Neuron. 2000 Oct;28(1):165-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11086992 11086992]
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Single protein]]
 
[[Category: Beich-Frandsen, M.]]
[[Category: Beich-Frandsen, M.]]
[[Category: Gajhede, M.]]
[[Category: Gajhede, M.]]
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[[Category: Transport]]
[[Category: Transport]]
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Revision as of 16:34, 17 February 2009

Template:STRUCTURE 3bft

Structure of the ligand-binding core of GluR2 in complex with the agonist (S)-TDPA at 2.25 A resolution

Template:ABSTRACT PUBMED 18269227

About this Structure

3BFT is a 3 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Beich-Frandsen M, Pickering DS, Mirza O, Johansen TN, Greenwood J, Vestergaard B, Schousboe A, Gajhede M, Liljefors T, Kastrup JS. Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. J Med Chem. 2008 Mar 13;51(5):1459-63. Epub 2008 Feb 13. PMID:18269227 doi:10.1021/jm701126w
  • Armstrong N, Gouaux E. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron. 2000 Oct;28(1):165-81. PMID:11086992

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