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2fzp

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==About this Structure==
==About this Structure==
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2FZP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FZP OCA].
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2FZP is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FZP OCA].
==Reference==
==Reference==
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Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8)., Avvakumov GV, Walker JR, Xue S, Finerty PJ Jr, Mackenzie F, Newman EM, Dhe-Paganon S, J Biol Chem. 2006 Dec 8;281(49):38061-70. Epub 2006 Oct 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17035239 17035239]
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<ref group="xtra">PMID:17035239</ref><ref group="xtra">PMID:15314180</ref><ref group="xtra">PMID:14765125</ref><ref group="xtra">PMID:11867753</ref><ref group="xtra">PMID:11358394</ref><references group="xtra"/>
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Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8., Wu X, Yen L, Irwin L, Sweeney C, Carraway KL 3rd, Mol Cell Biol. 2004 Sep;24(17):7748-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15314180 15314180]
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Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis., Qiu XB, Markant SL, Yuan J, Goldberg AL, EMBO J. 2004 Feb 25;23(4):800-10. Epub 2004 Feb 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14765125 14765125]
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An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels., Diamonti AJ, Guy PM, Ivanof C, Wong K, Sweeney C, Carraway KL 3rd, Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2866-71. Epub 2002 Feb 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11867753 11867753]
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FLRF, a novel evolutionarily conserved RING finger gene, is differentially expressed in mouse fetal and adult hematopoietic stem cells and progenitors., Abdullah JM, Li X, Nachtman RG, Jurecic R, Blood Cells Mol Dis. 2001 Jan-Feb;27(1):320-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11358394 11358394]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Arrowsmith, C.]]
[[Category: Arrowsmith, C.]]
[[Category: Avvakumov, G V.]]
[[Category: Avvakumov, G V.]]
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[[Category: Structural genomics consortium]]
[[Category: Structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:37:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:44:15 2009''

Revision as of 17:44, 17 February 2009

Image:2fzp.png

Template:STRUCTURE 2fzp

Crystal structure of the USP8 interaction domain of human NRDP1

Template:ABSTRACT PUBMED 17035239

About this Structure

2FZP is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Avvakumov GV, Walker JR, Xue S, Finerty PJ Jr, Mackenzie F, Newman EM, Dhe-Paganon S. Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8). J Biol Chem. 2006 Dec 8;281(49):38061-70. Epub 2006 Oct 11. PMID:17035239 doi:10.1074/jbc.M606704200
  • Wu X, Yen L, Irwin L, Sweeney C, Carraway KL 3rd. Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8. Mol Cell Biol. 2004 Sep;24(17):7748-57. PMID:15314180 doi:10.1128/MCB.24.17.7748-7757.2004
  • Qiu XB, Markant SL, Yuan J, Goldberg AL. Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis. EMBO J. 2004 Feb 25;23(4):800-10. Epub 2004 Feb 12. PMID:14765125 doi:10.1038/sj.emboj.7600075
  • Diamonti AJ, Guy PM, Ivanof C, Wong K, Sweeney C, Carraway KL 3rd. An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2866-71. Epub 2002 Feb 26. PMID:11867753 doi:10.1073/pnas.052709799
  • Abdullah JM, Li X, Nachtman RG, Jurecic R. FLRF, a novel evolutionarily conserved RING finger gene, is differentially expressed in mouse fetal and adult hematopoietic stem cells and progenitors. Blood Cells Mol Dis. 2001 Jan-Feb;27(1):320-33. PMID:11358394 doi:10.1006/bcmd.2001.0390

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