3dbc

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==About this Structure==
==About this Structure==
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3DBC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBC OCA].
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3DBC is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBC OCA].
==Reference==
==Reference==
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Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors., Fucini RV, Hanan EJ, Romanowski MJ, Elling RA, Lew W, Barr KJ, Zhu J, Yoburn JC, Liu Y, Fahr BT, Fan J, Lu Y, Pham P, Choong IC, Vanderporten EC, Bui M, Purkey HE, Evanchik MJ, Yang W, Bioorg Med Chem Lett. 2008 Aug 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18793847 18793847]
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<ref group="xtra">PMID:18793847</ref><references group="xtra"/>
[[Category: Danio rerio]]
[[Category: Danio rerio]]
[[Category: Polo kinase]]
[[Category: Polo kinase]]
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[[Category: Single protein]]
 
[[Category: Barr, K J.]]
[[Category: Barr, K J.]]
[[Category: Elling, R A.]]
[[Category: Elling, R A.]]
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[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 5 10:45:40 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 23:42:47 2009''

Revision as of 21:42, 17 February 2009

Template:STRUCTURE 3dbc

Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 257

Template:ABSTRACT PUBMED 18793847

About this Structure

3DBC is a 1 chain structure of sequence from Danio rerio. Full crystallographic information is available from OCA.

Reference

  • Fucini RV, Hanan EJ, Romanowski MJ, Elling RA, Lew W, Barr KJ, Zhu J, Yoburn JC, Liu Y, Fahr BT, Fan J, Lu Y, Pham P, Choong IC, VanderPorten EC, Bui M, Purkey HE, Evanchik MJ, Yang W. Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5648-52. Epub 2008 Aug 29. PMID:18793847 doi:10.1016/j.bmcl.2008.08.095

Page seeded by OCA on Tue Feb 17 23:42:47 2009

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