2qy0

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==About this Structure==
==About this Structure==
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2QY0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QY0 OCA].
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2QY0 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QY0 OCA].
==Reference==
==Reference==
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Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r., Kardos J, Harmat V, Pallo A, Barabas O, Szilagyi K, Graf L, Naray-Szabo G, Goto Y, Zavodszky P, Gal P, Mol Immunol. 2008 Mar;45(6):1752-60. Epub 2007 Nov 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17996945 17996945]
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<ref group="xtra">PMID:17996945</ref><references group="xtra"/>
[[Category: Complement subcomponent C1r]]
[[Category: Complement subcomponent C1r]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Barabas, O.]]
[[Category: Barabas, O.]]
[[Category: Gal, P.]]
[[Category: Gal, P.]]
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[[Category: Sushi]]
[[Category: Sushi]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:12:14 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:34:44 2009''

Revision as of 00:34, 18 February 2009

Template:STRUCTURE 2qy0

Contents

Active dimeric structure of the catalytic domain of C1r reveals enzyme-product like contacts

Template:ABSTRACT PUBMED 17996945

Disease

Known disease associated with this structure: C1r/C1s deficiency, combined OMIM:[216950]

About this Structure

2QY0 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kardos J, Harmat V, Pallo A, Barabas O, Szilagyi K, Graf L, Naray-Szabo G, Goto Y, Zavodszky P, Gal P. Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r. Mol Immunol. 2008 Mar;45(6):1752-60. Epub 2007 Nov 9. PMID:17996945 doi:10.1016/j.molimm.2007.09.031

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