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2c2t

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==About this Structure==
==About this Structure==
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2C2T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C2T OCA].
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2C2T is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C2T OCA].
==Reference==
==Reference==
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Novel boron-containing, nonclassical antifolates: synthesis and preliminary biological and structural evaluation., Reynolds RC, Campbell SR, Fairchild RG, Kisliuk RL, Micca PL, Queener SF, Riordan JM, Sedwick WD, Waud WR, Leung AK, Dixon RW, Suling WJ, Borhani DW, J Med Chem. 2007 Jul 12;50(14):3283-9. Epub 2007 Jun 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17569517 17569517]
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<ref group="xtra">PMID:17569517</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Borhani, D W.]]
[[Category: Borhani, D W.]]
[[Category: Leung, A K.W.]]
[[Category: Leung, A K.W.]]
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[[Category: Reductase]]
[[Category: Reductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:41:12 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:00:40 2009''

Revision as of 01:00, 18 February 2009

Image:2c2t.png

Template:STRUCTURE 2c2t

HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 2,4-DIAMINO-5-((7,8-DICARBAUNDECABORAN-7-YL)METHYL)-6-METHYLPYRIMIDINE, A NOVEL BORON CONTAINING, NONCLASSICAL ANTIFOLATE

Template:ABSTRACT PUBMED 17569517

About this Structure

2C2T is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Reynolds RC, Campbell SR, Fairchild RG, Kisliuk RL, Micca PL, Queener SF, Riordan JM, Sedwick WD, Waud WR, Leung AK, Dixon RW, Suling WJ, Borhani DW. Novel boron-containing, nonclassical antifolates: synthesis and preliminary biological and structural evaluation. J Med Chem. 2007 Jul 12;50(14):3283-9. Epub 2007 Jun 15. PMID:17569517 doi:10.1021/jm0701977

Page seeded by OCA on Wed Feb 18 03:00:40 2009

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